Both PKA and Epac pathways mediate N-acetylcysteine-induced Connexin43 preservation in rats with myocardial infarction.
Cardiac remodeling was shown to be associated with reduced gap junction expression after myocardial infarction. A reduction in gap junctional proteins between myocytes may trigger ventricular arrhythmia. Therefore, we investigated whether N-acetylcysteine exerted antiarrhythmic effect by preserving...
Guardado en:
Autores principales: | Tsung-Ming Lee, Shinn-Zong Lin, Nen-Chung Chang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3c048d4d45e04455a67aba0af1af3f0b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Advances of Traditional Chinese Medicine Regulating Connexin43 in the Prevention and Treatment of Myocardial Infarction
por: Keke Liu, et al.
Publicado: (2021) -
Opposing roles of PKA and EPAC in the cAMP-dependent regulation of schwann cell proliferation and differentiation [corrected].
por: Ketty Bacallao, et al.
Publicado: (2013) -
Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism.
por: Holly A Cyphert, et al.
Publicado: (2014) -
Data on Connexin 43 hemichannels regulation of cellular redox in lens
por: Yumeng Quan, et al.
Publicado: (2021) -
Monoamine Oxidase-B Inhibitor Reduction in Pro-Inflammatory Cytokines Mediated by Inhibition of cAMP-PKA/EPAC Signaling
por: Edward E. Putnins, et al.
Publicado: (2021)