DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex

FG-Nups are disordered proteins in the nuclear pore complex (NPC) where they selectively control nuclear transport. Here authors build NPC-mimics based on DNA origami rings which attach a certain numbers of Nups to analyse those nanopores by cryoEM and conductance measurements.

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Autores principales:	Philip Ketterer, Adithya N. Ananth, Diederik S. Laman Trip, Ankur Mishra, Eva Bertosin, Mahipal Ganji, Jaco van der Torre, Patrick Onck, Hendrik Dietz, Cees Dekker
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3c16edd0fd33457389226bffa28bd552
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spelling	oai:doaj.org-article:3c16edd0fd33457389226bffa28bd5522021-12-02T16:56:53ZDNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex10.1038/s41467-018-03313-w2041-1723https://doaj.org/article/3c16edd0fd33457389226bffa28bd5522018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03313-whttps://doaj.org/toc/2041-1723FG-Nups are disordered proteins in the nuclear pore complex (NPC) where they selectively control nuclear transport. Here authors build NPC-mimics based on DNA origami rings which attach a certain numbers of Nups to analyse those nanopores by cryoEM and conductance measurements.Philip KettererAdithya N. AnanthDiederik S. Laman TripAnkur MishraEva BertosinMahipal GanjiJaco van der TorrePatrick OnckHendrik DietzCees DekkerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Philip Ketterer Adithya N. Ananth Diederik S. Laman Trip Ankur Mishra Eva Bertosin Mahipal Ganji Jaco van der Torre Patrick Onck Hendrik Dietz Cees Dekker DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
description	FG-Nups are disordered proteins in the nuclear pore complex (NPC) where they selectively control nuclear transport. Here authors build NPC-mimics based on DNA origami rings which attach a certain numbers of Nups to analyse those nanopores by cryoEM and conductance measurements.
format	article
author	Philip Ketterer Adithya N. Ananth Diederik S. Laman Trip Ankur Mishra Eva Bertosin Mahipal Ganji Jaco van der Torre Patrick Onck Hendrik Dietz Cees Dekker
author_facet	Philip Ketterer Adithya N. Ananth Diederik S. Laman Trip Ankur Mishra Eva Bertosin Mahipal Ganji Jaco van der Torre Patrick Onck Hendrik Dietz Cees Dekker
author_sort	Philip Ketterer
title	DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
title_short	DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
title_full	DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
title_fullStr	DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
title_full_unstemmed	DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
title_sort	dna origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3c16edd0fd33457389226bffa28bd552
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DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex

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