KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis

It is unclear whether there is a progenitor/stem cell in the basal layer of the urothelium in the bladder. Here, the authors identify Keratin14 positive cells that can regenerate the bladder in both a natural and injury-induced manner, and following neoplastic transformation, can give rise to tumour...

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Autores principales:	George Papafotiou, Varvara Paraskevopoulou, Eleni Vasilaki, Zoi Kanaki, Nikolaos Paschalidis, Apostolos Klinakis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3c1999e5eecd475a9dca9378568b6ec0
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spelling	oai:doaj.org-article:3c1999e5eecd475a9dca9378568b6ec02021-12-02T14:39:50ZKRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis10.1038/ncomms119142041-1723https://doaj.org/article/3c1999e5eecd475a9dca9378568b6ec02016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11914https://doaj.org/toc/2041-1723It is unclear whether there is a progenitor/stem cell in the basal layer of the urothelium in the bladder. Here, the authors identify Keratin14 positive cells that can regenerate the bladder in both a natural and injury-induced manner, and following neoplastic transformation, can give rise to tumours.George PapafotiouVarvara ParaskevopoulouEleni VasilakiZoi KanakiNikolaos PaschalidisApostolos KlinakisNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q George Papafotiou Varvara Paraskevopoulou Eleni Vasilaki Zoi Kanaki Nikolaos Paschalidis Apostolos Klinakis KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
description	It is unclear whether there is a progenitor/stem cell in the basal layer of the urothelium in the bladder. Here, the authors identify Keratin14 positive cells that can regenerate the bladder in both a natural and injury-induced manner, and following neoplastic transformation, can give rise to tumours.
format	article
author	George Papafotiou Varvara Paraskevopoulou Eleni Vasilaki Zoi Kanaki Nikolaos Paschalidis Apostolos Klinakis
author_facet	George Papafotiou Varvara Paraskevopoulou Eleni Vasilaki Zoi Kanaki Nikolaos Paschalidis Apostolos Klinakis
author_sort	George Papafotiou
title	KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
title_short	KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
title_full	KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
title_fullStr	KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
title_full_unstemmed	KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
title_sort	krt14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/3c1999e5eecd475a9dca9378568b6ec0
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KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis

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