Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon

T helper 2 (Th2) cell responses are essential for immunity against parasites, but how Th2 response is modulated in the gut is still unclear. Here the authors show that distinct dendritic cell subsets distinguishable by CD11b, CD103 and IRF4 function in the small intestine or colon to promote Th2 res...

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Autores principales:	Johannes U. Mayer, Mimoza Demiri, William W. Agace, Andrew S. MacDonald, Marcus Svensson-Frej, Simon W. Milling
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3c27826cbd534f9586aaa3ade5f87475
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spelling	oai:doaj.org-article:3c27826cbd534f9586aaa3ade5f874752021-12-02T17:06:27ZDifferent populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon10.1038/ncomms158202041-1723https://doaj.org/article/3c27826cbd534f9586aaa3ade5f874752017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15820https://doaj.org/toc/2041-1723T helper 2 (Th2) cell responses are essential for immunity against parasites, but how Th2 response is modulated in the gut is still unclear. Here the authors show that distinct dendritic cell subsets distinguishable by CD11b, CD103 and IRF4 function in the small intestine or colon to promote Th2 responses.Johannes U. MayerMimoza DemiriWilliam W. AgaceAndrew S. MacDonaldMarcus Svensson-FrejSimon W. MillingNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Johannes U. Mayer Mimoza Demiri William W. Agace Andrew S. MacDonald Marcus Svensson-Frej Simon W. Milling Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon
description	T helper 2 (Th2) cell responses are essential for immunity against parasites, but how Th2 response is modulated in the gut is still unclear. Here the authors show that distinct dendritic cell subsets distinguishable by CD11b, CD103 and IRF4 function in the small intestine or colon to promote Th2 responses.
format	article
author	Johannes U. Mayer Mimoza Demiri William W. Agace Andrew S. MacDonald Marcus Svensson-Frej Simon W. Milling
author_facet	Johannes U. Mayer Mimoza Demiri William W. Agace Andrew S. MacDonald Marcus Svensson-Frej Simon W. Milling
author_sort	Johannes U. Mayer
title	Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon
title_short	Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon
title_full	Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon
title_fullStr	Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon
title_full_unstemmed	Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon
title_sort	different populations of cd11b+ dendritic cells drive th2 responses in the small intestine and colon
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3c27826cbd534f9586aaa3ade5f87475
work_keys_str_mv	AT johannesumayer differentpopulationsofcd11bdendriticcellsdriveth2responsesinthesmallintestineandcolon AT mimozademiri differentpopulationsofcd11bdendriticcellsdriveth2responsesinthesmallintestineandcolon AT williamwagace differentpopulationsofcd11bdendriticcellsdriveth2responsesinthesmallintestineandcolon AT andrewsmacdonald differentpopulationsofcd11bdendriticcellsdriveth2responsesinthesmallintestineandcolon AT marcussvenssonfrej differentpopulationsofcd11bdendriticcellsdriveth2responsesinthesmallintestineandcolon AT simonwmilling differentpopulationsofcd11bdendriticcellsdriveth2responsesinthesmallintestineandcolon
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Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon

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