Parental relatedness through time revealed by runs of homozygosity in ancient DNA

Little is known about how human parental relatedness varied across ancient populations. Runs of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH in ancient genomes and infer low rates of close kin unions across most ancient populations....

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Autores principales: Harald Ringbauer, John Novembre, Matthias Steinrücken
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3c375c21a4024b49900aa78e6f0bd1ef
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spelling oai:doaj.org-article:3c375c21a4024b49900aa78e6f0bd1ef2021-12-02T17:24:13ZParental relatedness through time revealed by runs of homozygosity in ancient DNA10.1038/s41467-021-25289-w2041-1723https://doaj.org/article/3c375c21a4024b49900aa78e6f0bd1ef2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25289-whttps://doaj.org/toc/2041-1723Little is known about how human parental relatedness varied across ancient populations. Runs of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH in ancient genomes and infer low rates of close kin unions across most ancient populations.Harald RingbauerJohn NovembreMatthias SteinrückenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Harald Ringbauer
John Novembre
Matthias Steinrücken
Parental relatedness through time revealed by runs of homozygosity in ancient DNA
description Little is known about how human parental relatedness varied across ancient populations. Runs of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH in ancient genomes and infer low rates of close kin unions across most ancient populations.
format article
author Harald Ringbauer
John Novembre
Matthias Steinrücken
author_facet Harald Ringbauer
John Novembre
Matthias Steinrücken
author_sort Harald Ringbauer
title Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_short Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_full Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_fullStr Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_full_unstemmed Parental relatedness through time revealed by runs of homozygosity in ancient DNA
title_sort parental relatedness through time revealed by runs of homozygosity in ancient dna
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3c375c21a4024b49900aa78e6f0bd1ef
work_keys_str_mv AT haraldringbauer parentalrelatednessthroughtimerevealedbyrunsofhomozygosityinancientdna
AT johnnovembre parentalrelatednessthroughtimerevealedbyrunsofhomozygosityinancientdna
AT matthiassteinrucken parentalrelatednessthroughtimerevealedbyrunsofhomozygosityinancientdna
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