Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration

Abstract Retinal Ganglion Cells (RGCs) lose their ability to grow axons during development. Adult RGCs thus fail to regenerate their axons after injury, leading to vision loss. To uncover mechanisms that promote regeneration of RGC axons, we identified transcription factors (TF) and open chromatin r...

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Auteurs principaux: Wolfgang Pita-Thomas, Tassia Mangetti Gonçalves, Ajeet Kumar, Guoyan Zhao, Valeria Cavalli
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/3c37702a6f1543b5968d79e033cbdc1b
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