Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration
Abstract Retinal Ganglion Cells (RGCs) lose their ability to grow axons during development. Adult RGCs thus fail to regenerate their axons after injury, leading to vision loss. To uncover mechanisms that promote regeneration of RGC axons, we identified transcription factors (TF) and open chromatin r...
Enregistré dans:
Auteurs principaux: | Wolfgang Pita-Thomas, Tassia Mangetti Gonçalves, Ajeet Kumar, Guoyan Zhao, Valeria Cavalli |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/3c37702a6f1543b5968d79e033cbdc1b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism
par: Eric E. Ewan, et autres
Publié: (2021) -
Spatially mapped single-cell chromatin accessibility
par: Casey A. Thornton, et autres
Publié: (2021) -
Genome-wide chromatin accessibility is restricted by ANP32E
par: Kristin E. Murphy, et autres
Publié: (2020) -
Genome-wide mapping of DNase I hypersensitive sites reveals chromatin accessibility changes in Arabidopsis euchromatin and heterochromatin regions under extended darkness
par: Yue Liu, et autres
Publié: (2017) -
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas
par: Karolina Stępniak, et autres
Publié: (2021)