Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction
Metabolic reprogramming during Dietary Restriction (DR) activates cytoprotective gene expression. Here the authors show that PUFAs generated during DR signal via the p38-MAPK pathway to enhance cytoprotective gene expression, contributing to increased longevity.
Guardado en:
Autores principales: | Manish Chamoli, Anita Goyala, Syed Shamsh Tabrez, Atif Ahmed Siddiqui, Anupama Singh, Adam Antebi, Gordon J. Lithgow, Jennifer L. Watts, Arnab Mukhopadhyay |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3c37c1fd9a7048f1bb216609bd91f5e7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity
por: Syed Shamsh Tabrez, et al.
Publicado: (2017) -
Immunomodulatory Nanoparticles Mitigate Macrophage Inflammation via Inhibition of PAMP Interactions and Lactate-Mediated Functional Reprogramming of NF-κB and p38 MAPK
por: Jackline Joy Martín Lasola, et al.
Publicado: (2021) -
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas
por: Shuman Wang, et al.
Publicado: (2021) -
p38 MAPK inhibition reduces diabetes-induced impairment of wound healing
por: Satyanarayana Medicherla, et al.
Publicado: (2009) -
The promising therapeutic potentials of ginsenosides mediated through p38 MAPK signaling inhibition
por: El-Shaimaa A. Arafa, et al.
Publicado: (2021)