Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation

Mutations in the chloride channel ClC-2 have been associated with familial forms of hyperaldosteronism. Here, Schewe et al. generated a mouse model carrying the most common mutation found in patients and find it recapitulates key features of the disease, providing a unique tool for future studies on...

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Autores principales: Julia Schewe, Eric Seidel, Sofia Forslund, Lajos Marko, Jörg Peters, Dominik N. Muller, Christoph Fahlke, Gabriel Stölting, Ute Scholl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3c3f88638ed74e3884f98fb595b7139e
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