Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer
Senescence is a cellular state in which cells undergo persistent cell cycle arrest in response to nonlethal stress. In the treatment of cancer, senescence induction is a potent method of suppressing tumour cell proliferation. In spite of this, senescent cancer cells and adjacent nontransformed cells...
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Main Authors: | Cecilia R. Chambers, Shona Ritchie, Brooke A. Pereira, Paul Timpson |
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Format: | article |
Language: | EN |
Published: |
Wiley
2021
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Online Access: | https://doaj.org/article/3c42425e58964fee97e18d1c95d1e7dd |
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