Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period

Aim. To identify factors responsible for the early development of microvascular complications in patients with type 1 diabetes mellitus (DM1)and to evaluate dependence of their prevalence on the type of insulin. Materials and methods. The study carried out from May 2002 to November 2007 included a...

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Autores principales:	Lyubov' Leonidovna Bolotskaya, Yury Ivanovich Suntsov, Igor Vladislavovich Kazakov, Marina Vladimirovna Shestakova, Ivan Ivanovich Dedov
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2009
Materias:	state diabetes registry glycated hemoglobin one-step epidemiological survey insulin analogs diabetic nephropathy diabetic retinopathy diabetic foot syndrome delayed physical development Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/3c4494d28b2e46889fe6ad97da38d647
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spelling	oai:doaj.org-article:3c4494d28b2e46889fe6ad97da38d6472021-11-14T09:00:14ZEfficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period2072-03512072-037810.14341/2072-0351-5452https://doaj.org/article/3c4494d28b2e46889fe6ad97da38d6472009-09-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5452https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To identify factors responsible for the early development of microvascular complications in patients with type 1 diabetes mellitus (DM1)and to evaluate dependence of their prevalence on the type of insulin. Materials and methods. The study carried out from May 2002 to November 2007 included a random sample of patients with DM1 over 10 years in duration(n=5895, 100%, >=20 years) from the Central, Volga, Ural, Siberian, North-West and Southern federal districts. All patients underwentexamination of eye fundus and feet, measurement of microalbuminuria, creatinine, urea, serum lipid spectrum and HbА1с. Results. Mean HbА1с level in patients of group 1 (using insulin analogs) was significantly lower than in group 2 (using homan insulin) (Me 8,5?0,2%;9,7?0,4% SD* respectively) p>0,01. Mean daily insulin dose in group 1 and 2 was >1,0 andLyubov' Leonidovna BolotskayaYury Ivanovich SuntsovIgor Vladislavovich KazakovMarina Vladimirovna ShestakovaIvan Ivanovich DedovEndocrinology Research Centrearticlestate diabetes registryglycated hemoglobinone-step epidemiological surveyinsulin analogsdiabetic nephropathydiabetic retinopathydiabetic foot syndromedelayed physical developmentNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 12, Iss 3, Pp 49-52 (2009)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	state diabetes registry glycated hemoglobin one-step epidemiological survey insulin analogs diabetic nephropathy diabetic retinopathy diabetic foot syndrome delayed physical development Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	state diabetes registry glycated hemoglobin one-step epidemiological survey insulin analogs diabetic nephropathy diabetic retinopathy diabetic foot syndrome delayed physical development Nutritional diseases. Deficiency diseases RC620-627 Lyubov' Leonidovna Bolotskaya Yury Ivanovich Suntsov Igor Vladislavovich Kazakov Marina Vladimirovna Shestakova Ivan Ivanovich Dedov Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period
description	Aim. To identify factors responsible for the early development of microvascular complications in patients with type 1 diabetes mellitus (DM1)and to evaluate dependence of their prevalence on the type of insulin. Materials and methods. The study carried out from May 2002 to November 2007 included a random sample of patients with DM1 over 10 years in duration(n=5895, 100%, >=20 years) from the Central, Volga, Ural, Siberian, North-West and Southern federal districts. All patients underwentexamination of eye fundus and feet, measurement of microalbuminuria, creatinine, urea, serum lipid spectrum and HbА1с. Results. Mean HbА1с level in patients of group 1 (using insulin analogs) was significantly lower than in group 2 (using homan insulin) (Me 8,5?0,2%;9,7?0,4% SD* respectively) p>0,01. Mean daily insulin dose in group 1 and 2 was >1,0 and
format	article
author	Lyubov' Leonidovna Bolotskaya Yury Ivanovich Suntsov Igor Vladislavovich Kazakov Marina Vladimirovna Shestakova Ivan Ivanovich Dedov
author_facet	Lyubov' Leonidovna Bolotskaya Yury Ivanovich Suntsov Igor Vladislavovich Kazakov Marina Vladimirovna Shestakova Ivan Ivanovich Dedov
author_sort	Lyubov' Leonidovna Bolotskaya
title	Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period
title_short	Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period
title_full	Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period
title_fullStr	Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period
title_full_unstemmed	Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period
title_sort	efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period
publisher	Endocrinology Research Centre
publishDate	2009
url	https://doaj.org/article/3c4494d28b2e46889fe6ad97da38d647
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Efficiency of insulin analogs in young patients with type 1 diabetes mellitus debut during pubertal period

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