Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy

Despite the continuous development of medical devices and the standardization of gastrectomy plus D2 lymph node dissection, advanced gastric cancer still has high distant metastasis rate and local recurrence rate, and the prognosis is poor. Neoadjuvant chemotherapy can improve the long-term survival...

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Autores principales:	SUN Chongyuan, ZHAO Dongbing
Formato:	article
Lenguaje:	ZH
Publicado:	Magazine House of Cancer Research on Prevention and Treatment 2021
Materias:	gastric cancer neoadjuvant chemotherapy operative complication risk factors Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/3c4c108a45c94a409800d9abf2f3ea30
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spelling	oai:doaj.org-article:3c4c108a45c94a409800d9abf2f3ea302021-12-03T09:25:17ZCharacteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy1000-857810.3971/j.issn.1000-8578.2021.21.0508https://doaj.org/article/3c4c108a45c94a409800d9abf2f3ea302021-11-01T00:00:00Zhttp://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2021.21.0508https://doaj.org/toc/1000-8578Despite the continuous development of medical devices and the standardization of gastrectomy plus D2 lymph node dissection, advanced gastric cancer still has high distant metastasis rate and local recurrence rate, and the prognosis is poor. Neoadjuvant chemotherapy can improve the long-term survival of patients with advanced gastric cancer by reducing tumor stage, increasing R0 resection rate and eliminating potential micrometastasis. However, it is still the focus of concern that whether the adverse reactions of preoperative chemotherapy will increase the incidence of postoperative complications. Postoperative complications can affect the oncological outcomes by activating minimal residual lesions and promoting metastasis through related inflammatory changes or delaying adjuvant therapy, so the premise of wide application of neoadjuvant chemotherapy should be the guarantee of surgical safety. This article reviews the incidence, severity and prognosis of operative complications in gastric cancer patients after neoadjuvant chemotherapy and further explores its influencing factors.SUN ChongyuanZHAO DongbingMagazine House of Cancer Research on Prevention and Treatmentarticlegastric cancerneoadjuvant chemotherapyoperative complicationrisk factorsNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ZHZhongliu Fangzhi Yanjiu, Vol 48, Iss 11, Pp 1046-1051 (2021)
institution	DOAJ
collection	DOAJ
language	ZH
topic	gastric cancer neoadjuvant chemotherapy operative complication risk factors Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	gastric cancer neoadjuvant chemotherapy operative complication risk factors Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 SUN Chongyuan ZHAO Dongbing Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy
description	Despite the continuous development of medical devices and the standardization of gastrectomy plus D2 lymph node dissection, advanced gastric cancer still has high distant metastasis rate and local recurrence rate, and the prognosis is poor. Neoadjuvant chemotherapy can improve the long-term survival of patients with advanced gastric cancer by reducing tumor stage, increasing R0 resection rate and eliminating potential micrometastasis. However, it is still the focus of concern that whether the adverse reactions of preoperative chemotherapy will increase the incidence of postoperative complications. Postoperative complications can affect the oncological outcomes by activating minimal residual lesions and promoting metastasis through related inflammatory changes or delaying adjuvant therapy, so the premise of wide application of neoadjuvant chemotherapy should be the guarantee of surgical safety. This article reviews the incidence, severity and prognosis of operative complications in gastric cancer patients after neoadjuvant chemotherapy and further explores its influencing factors.
format	article
author	SUN Chongyuan ZHAO Dongbing
author_facet	SUN Chongyuan ZHAO Dongbing
author_sort	SUN Chongyuan
title	Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy
title_short	Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy
title_full	Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy
title_fullStr	Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy
title_full_unstemmed	Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy
title_sort	characteristics and risk factors of postoperative complications in gastric cancer patients treated with neoadjuvant chemotherapy
publisher	Magazine House of Cancer Research on Prevention and Treatment
publishDate	2021
url	https://doaj.org/article/3c4c108a45c94a409800d9abf2f3ea30
work_keys_str_mv	AT sunchongyuan characteristicsandriskfactorsofpostoperativecomplicationsingastriccancerpatientstreatedwithneoadjuvantchemotherapy AT zhaodongbing characteristicsandriskfactorsofpostoperativecomplicationsingastriccancerpatientstreatedwithneoadjuvantchemotherapy
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Characteristics and Risk Factors of Postoperative Complications in Gastric Cancer Patients Treated with Neoadjuvant Chemotherapy

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