Maintenance of Complex Trait Variation: Classic Theory and Modern Data

Numerous studies have found evidence that GWAS loci experience negative selection, which increases in intensity with the effect size of identified variants. However, there is also accumulating evidence that this selection is not entirely mediated by the focal trait and contains a substantial pleiotr...

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Détails bibliographiques
Auteurs principaux: Evan M. Koch, Shamil R. Sunyaev
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/3c50ac8de3484bfab77b15b9934cc6ab
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