Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium
A novel and highly sensitive immunochromatographic strip based on a monoclonal antibody (3A9) was developed for the detection of cadmium in tap water. The 50% inhibition concentration of the antibody, which showed no cross-reactivity with other heavy metal ions, was 0.45 ng/mL and it recognized Cd(I...
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Taylor & Francis Group
2018
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oai:doaj.org-article:3c51fc5cf87b4d378d3a89581d87e9742021-11-26T11:19:46ZImmunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium0954-01051465-344310.1080/09540105.2017.1354358https://doaj.org/article/3c51fc5cf87b4d378d3a89581d87e9742018-01-01T00:00:00Zhttp://dx.doi.org/10.1080/09540105.2017.1354358https://doaj.org/toc/0954-0105https://doaj.org/toc/1465-3443A novel and highly sensitive immunochromatographic strip based on a monoclonal antibody (3A9) was developed for the detection of cadmium in tap water. The 50% inhibition concentration of the antibody, which showed no cross-reactivity with other heavy metal ions, was 0.45 ng/mL and it recognized Cd(II)–1-(4-isothiocyanobenzyl) ethylenediamine-N,N,N′,N′-tetraacetic acid (EDTA) (Cd(II)–ITCBE) and not metal-free ITCBE and EDTA. The cutoff value for semi-quantitative detection of the strip was 5 ng/mL and the lower limit of detection for quantitative detection was 0.2 ng/mL using a scanning reader. The percent recovery ranged from 107.6% to 132% in tap water samples.Shanshan SongShuzhen ZouJianping ZhuLiqiang LiuHua KuangTaylor & Francis Grouparticlecadmiumimmunochromatographic stripmonoclonal antibodygold-nanoparticle (gnp)Agriculture (General)S1-972Immunologic diseases. AllergyRC581-607ENFood and Agricultural Immunology, Vol 29, Iss 1, Pp 3-13 (2018) |
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DOAJ |
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cadmium immunochromatographic strip monoclonal antibody gold-nanoparticle (gnp) Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 |
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cadmium immunochromatographic strip monoclonal antibody gold-nanoparticle (gnp) Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 Shanshan Song Shuzhen Zou Jianping Zhu Liqiang Liu Hua Kuang Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
description |
A novel and highly sensitive immunochromatographic strip based on a monoclonal antibody (3A9) was developed for the detection of cadmium in tap water. The 50% inhibition concentration of the antibody, which showed no cross-reactivity with other heavy metal ions, was 0.45 ng/mL and it recognized Cd(II)–1-(4-isothiocyanobenzyl) ethylenediamine-N,N,N′,N′-tetraacetic acid (EDTA) (Cd(II)–ITCBE) and not metal-free ITCBE and EDTA. The cutoff value for semi-quantitative detection of the strip was 5 ng/mL and the lower limit of detection for quantitative detection was 0.2 ng/mL using a scanning reader. The percent recovery ranged from 107.6% to 132% in tap water samples. |
format |
article |
author |
Shanshan Song Shuzhen Zou Jianping Zhu Liqiang Liu Hua Kuang |
author_facet |
Shanshan Song Shuzhen Zou Jianping Zhu Liqiang Liu Hua Kuang |
author_sort |
Shanshan Song |
title |
Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
title_short |
Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
title_full |
Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
title_fullStr |
Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
title_full_unstemmed |
Immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
title_sort |
immunochromatographic paper sensor for ultrasensitive colorimetric detection of cadmium |
publisher |
Taylor & Francis Group |
publishDate |
2018 |
url |
https://doaj.org/article/3c51fc5cf87b4d378d3a89581d87e974 |
work_keys_str_mv |
AT shanshansong immunochromatographicpapersensorforultrasensitivecolorimetricdetectionofcadmium AT shuzhenzou immunochromatographicpapersensorforultrasensitivecolorimetricdetectionofcadmium AT jianpingzhu immunochromatographicpapersensorforultrasensitivecolorimetricdetectionofcadmium AT liqiangliu immunochromatographicpapersensorforultrasensitivecolorimetricdetectionofcadmium AT huakuang immunochromatographicpapersensorforultrasensitivecolorimetricdetectionofcadmium |
_version_ |
1718409528691654656 |