Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis

Background. As the spectrum of ophthalmic diseases keeps changing, uveitis has gradually become one of the major blinding eye diseases in the world. In recent years, it has become a research hotspot to select effective components for uveitis treatment from natural drugs. Methods. We searched PubMed...

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Autores principales:	Sicong Li, Fang Liu, Kai Zhang, Yujia Tong, Xin Liu
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/3c52a0440e004a76a6655401f26648f7
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spelling	oai:doaj.org-article:3c52a0440e004a76a6655401f26648f72021-11-15T01:20:10ZResearch Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis2314-715610.1155/2021/6683411https://doaj.org/article/3c52a0440e004a76a6655401f26648f72021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6683411https://doaj.org/toc/2314-7156Background. As the spectrum of ophthalmic diseases keeps changing, uveitis has gradually become one of the major blinding eye diseases in the world. In recent years, it has become a research hotspot to select effective components for uveitis treatment from natural drugs. Methods. We searched PubMed and EMBASE databases for studies written in English as well as Chinese National Knowledge Infrastructure (CNKI), CQVIP, and Wan Fang database for studies written in Chinese (inception through 30 December 2020). Results. Eight kinds of natural product ingredients were included in this article. They were found to not only regulate the expression of cytokines, proliferation, and differentiation of T help cells but also inhibit the damage of cytokines and inflammatory cells to uvea, blood aqueous barrier, and blood retinal barrier. Conclusion. Natural product ingredients have their unique advantages in the treatment of uveitis. They have good anti-inflammatory effects without causing serious adverse reactions, which enables them to be promising choices for preventive and therapeutic strategy of uveitis.Sicong LiFang LiuKai ZhangYujia TongXin LiuHindawi LimitedarticleImmunologic diseases. AllergyRC581-607ENJournal of Immunology Research, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607
spellingShingle	Immunologic diseases. Allergy RC581-607 Sicong Li Fang Liu Kai Zhang Yujia Tong Xin Liu Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis
description	Background. As the spectrum of ophthalmic diseases keeps changing, uveitis has gradually become one of the major blinding eye diseases in the world. In recent years, it has become a research hotspot to select effective components for uveitis treatment from natural drugs. Methods. We searched PubMed and EMBASE databases for studies written in English as well as Chinese National Knowledge Infrastructure (CNKI), CQVIP, and Wan Fang database for studies written in Chinese (inception through 30 December 2020). Results. Eight kinds of natural product ingredients were included in this article. They were found to not only regulate the expression of cytokines, proliferation, and differentiation of T help cells but also inhibit the damage of cytokines and inflammatory cells to uvea, blood aqueous barrier, and blood retinal barrier. Conclusion. Natural product ingredients have their unique advantages in the treatment of uveitis. They have good anti-inflammatory effects without causing serious adverse reactions, which enables them to be promising choices for preventive and therapeutic strategy of uveitis.
format	article
author	Sicong Li Fang Liu Kai Zhang Yujia Tong Xin Liu
author_facet	Sicong Li Fang Liu Kai Zhang Yujia Tong Xin Liu
author_sort	Sicong Li
title	Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis
title_short	Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis
title_full	Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis
title_fullStr	Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis
title_full_unstemmed	Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis
title_sort	research progress on the mechanism of natural product ingredients in the treatment of uveitis
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/3c52a0440e004a76a6655401f26648f7
work_keys_str_mv	AT sicongli researchprogressonthemechanismofnaturalproductingredientsinthetreatmentofuveitis AT fangliu researchprogressonthemechanismofnaturalproductingredientsinthetreatmentofuveitis AT kaizhang researchprogressonthemechanismofnaturalproductingredientsinthetreatmentofuveitis AT yujiatong researchprogressonthemechanismofnaturalproductingredientsinthetreatmentofuveitis AT xinliu researchprogressonthemechanismofnaturalproductingredientsinthetreatmentofuveitis
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Research Progress on the Mechanism of Natural Product Ingredients in the Treatment of Uveitis

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