Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure
Viral capsids need to protect the genome against harsh environmental conditions and cope with high internal pressure from the packaged genome. Here, the authors determine the structure of the thermostable phage P74-26 capsid at 2.8-Å resolution and identify features underlying enhanced capsid capaci...
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Nature Portfolio
2019
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oai:doaj.org-article:3c52f833affb4893b605b3ae7c48faca2021-12-02T14:39:42ZPrinciples for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure10.1038/s41467-019-12341-z2041-1723https://doaj.org/article/3c52f833affb4893b605b3ae7c48faca2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12341-zhttps://doaj.org/toc/2041-1723Viral capsids need to protect the genome against harsh environmental conditions and cope with high internal pressure from the packaged genome. Here, the authors determine the structure of the thermostable phage P74-26 capsid at 2.8-Å resolution and identify features underlying enhanced capsid capacity and structural stability.Nicholas P. StoneGabriel DemoEmily AgnelloBrian A. KelchNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Nicholas P. Stone Gabriel Demo Emily Agnello Brian A. Kelch Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure |
description |
Viral capsids need to protect the genome against harsh environmental conditions and cope with high internal pressure from the packaged genome. Here, the authors determine the structure of the thermostable phage P74-26 capsid at 2.8-Å resolution and identify features underlying enhanced capsid capacity and structural stability. |
format |
article |
author |
Nicholas P. Stone Gabriel Demo Emily Agnello Brian A. Kelch |
author_facet |
Nicholas P. Stone Gabriel Demo Emily Agnello Brian A. Kelch |
author_sort |
Nicholas P. Stone |
title |
Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure |
title_short |
Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure |
title_full |
Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure |
title_fullStr |
Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure |
title_full_unstemmed |
Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure |
title_sort |
principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/3c52f833affb4893b605b3ae7c48faca |
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_version_ |
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