A deep-learning framework for multi-level peptide–protein interaction prediction

Peptide-protein interactions play fundamental roles in cellular processes and are crucial for designing peptide therapeutics. Here, the authors present a deep learning framework for simultaneously predicting peptide-protein interactions and identifying peptide binding residues involved in the intera...

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Autores principales: Yipin Lei, Shuya Li, Ziyi Liu, Fangping Wan, Tingzhong Tian, Shao Li, Dan Zhao, Jianyang Zeng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3c57279c8dca432e92343f39c256dd79
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spelling oai:doaj.org-article:3c57279c8dca432e92343f39c256dd792021-12-02T18:02:16ZA deep-learning framework for multi-level peptide–protein interaction prediction10.1038/s41467-021-25772-42041-1723https://doaj.org/article/3c57279c8dca432e92343f39c256dd792021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25772-4https://doaj.org/toc/2041-1723Peptide-protein interactions play fundamental roles in cellular processes and are crucial for designing peptide therapeutics. Here, the authors present a deep learning framework for simultaneously predicting peptide-protein interactions and identifying peptide binding residues involved in the interactions.Yipin LeiShuya LiZiyi LiuFangping WanTingzhong TianShao LiDan ZhaoJianyang ZengNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yipin Lei
Shuya Li
Ziyi Liu
Fangping Wan
Tingzhong Tian
Shao Li
Dan Zhao
Jianyang Zeng
A deep-learning framework for multi-level peptide–protein interaction prediction
description Peptide-protein interactions play fundamental roles in cellular processes and are crucial for designing peptide therapeutics. Here, the authors present a deep learning framework for simultaneously predicting peptide-protein interactions and identifying peptide binding residues involved in the interactions.
format article
author Yipin Lei
Shuya Li
Ziyi Liu
Fangping Wan
Tingzhong Tian
Shao Li
Dan Zhao
Jianyang Zeng
author_facet Yipin Lei
Shuya Li
Ziyi Liu
Fangping Wan
Tingzhong Tian
Shao Li
Dan Zhao
Jianyang Zeng
author_sort Yipin Lei
title A deep-learning framework for multi-level peptide–protein interaction prediction
title_short A deep-learning framework for multi-level peptide–protein interaction prediction
title_full A deep-learning framework for multi-level peptide–protein interaction prediction
title_fullStr A deep-learning framework for multi-level peptide–protein interaction prediction
title_full_unstemmed A deep-learning framework for multi-level peptide–protein interaction prediction
title_sort deep-learning framework for multi-level peptide–protein interaction prediction
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3c57279c8dca432e92343f39c256dd79
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