Analytic framework for peptidomics applied to large-scale neuropeptide identification
Neuropeptide research is challenged by technical difficulties in identifying new bioactive peptides. Here the authors present an analytical pipeline for large-scale peptidomics applied to the rat hypothalamus, identifying thousands of endogenous neuropeptides and their post-translational modificatio...
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Nature Portfolio
2016
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oai:doaj.org-article:3c5d7d3bb3cc41ce8dc8f62c4a6c9d282021-12-02T17:32:38ZAnalytic framework for peptidomics applied to large-scale neuropeptide identification10.1038/ncomms114362041-1723https://doaj.org/article/3c5d7d3bb3cc41ce8dc8f62c4a6c9d282016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11436https://doaj.org/toc/2041-1723Neuropeptide research is challenged by technical difficulties in identifying new bioactive peptides. Here the authors present an analytical pipeline for large-scale peptidomics applied to the rat hypothalamus, identifying thousands of endogenous neuropeptides and their post-translational modifications.Anna SecherChristian D. KelstrupKilian W. Conde-FrieboesCharles PykeKirsten RaunBirgitte S. WulffJesper V. OlsenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Anna Secher Christian D. Kelstrup Kilian W. Conde-Frieboes Charles Pyke Kirsten Raun Birgitte S. Wulff Jesper V. Olsen Analytic framework for peptidomics applied to large-scale neuropeptide identification |
description |
Neuropeptide research is challenged by technical difficulties in identifying new bioactive peptides. Here the authors present an analytical pipeline for large-scale peptidomics applied to the rat hypothalamus, identifying thousands of endogenous neuropeptides and their post-translational modifications. |
format |
article |
author |
Anna Secher Christian D. Kelstrup Kilian W. Conde-Frieboes Charles Pyke Kirsten Raun Birgitte S. Wulff Jesper V. Olsen |
author_facet |
Anna Secher Christian D. Kelstrup Kilian W. Conde-Frieboes Charles Pyke Kirsten Raun Birgitte S. Wulff Jesper V. Olsen |
author_sort |
Anna Secher |
title |
Analytic framework for peptidomics applied to large-scale neuropeptide identification |
title_short |
Analytic framework for peptidomics applied to large-scale neuropeptide identification |
title_full |
Analytic framework for peptidomics applied to large-scale neuropeptide identification |
title_fullStr |
Analytic framework for peptidomics applied to large-scale neuropeptide identification |
title_full_unstemmed |
Analytic framework for peptidomics applied to large-scale neuropeptide identification |
title_sort |
analytic framework for peptidomics applied to large-scale neuropeptide identification |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/3c5d7d3bb3cc41ce8dc8f62c4a6c9d28 |
work_keys_str_mv |
AT annasecher analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification AT christiandkelstrup analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification AT kilianwcondefrieboes analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification AT charlespyke analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification AT kirstenraun analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification AT birgitteswulff analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification AT jespervolsen analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification |
_version_ |
1718380242197807104 |