Analytic framework for peptidomics applied to large-scale neuropeptide identification

Neuropeptide research is challenged by technical difficulties in identifying new bioactive peptides. Here the authors present an analytical pipeline for large-scale peptidomics applied to the rat hypothalamus, identifying thousands of endogenous neuropeptides and their post-translational modificatio...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Anna Secher, Christian D. Kelstrup, Kilian W. Conde-Frieboes, Charles Pyke, Kirsten Raun, Birgitte S. Wulff, Jesper V. Olsen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/3c5d7d3bb3cc41ce8dc8f62c4a6c9d28
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:3c5d7d3bb3cc41ce8dc8f62c4a6c9d28
record_format dspace
spelling oai:doaj.org-article:3c5d7d3bb3cc41ce8dc8f62c4a6c9d282021-12-02T17:32:38ZAnalytic framework for peptidomics applied to large-scale neuropeptide identification10.1038/ncomms114362041-1723https://doaj.org/article/3c5d7d3bb3cc41ce8dc8f62c4a6c9d282016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11436https://doaj.org/toc/2041-1723Neuropeptide research is challenged by technical difficulties in identifying new bioactive peptides. Here the authors present an analytical pipeline for large-scale peptidomics applied to the rat hypothalamus, identifying thousands of endogenous neuropeptides and their post-translational modifications.Anna SecherChristian D. KelstrupKilian W. Conde-FrieboesCharles PykeKirsten RaunBirgitte S. WulffJesper V. OlsenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anna Secher
Christian D. Kelstrup
Kilian W. Conde-Frieboes
Charles Pyke
Kirsten Raun
Birgitte S. Wulff
Jesper V. Olsen
Analytic framework for peptidomics applied to large-scale neuropeptide identification
description Neuropeptide research is challenged by technical difficulties in identifying new bioactive peptides. Here the authors present an analytical pipeline for large-scale peptidomics applied to the rat hypothalamus, identifying thousands of endogenous neuropeptides and their post-translational modifications.
format article
author Anna Secher
Christian D. Kelstrup
Kilian W. Conde-Frieboes
Charles Pyke
Kirsten Raun
Birgitte S. Wulff
Jesper V. Olsen
author_facet Anna Secher
Christian D. Kelstrup
Kilian W. Conde-Frieboes
Charles Pyke
Kirsten Raun
Birgitte S. Wulff
Jesper V. Olsen
author_sort Anna Secher
title Analytic framework for peptidomics applied to large-scale neuropeptide identification
title_short Analytic framework for peptidomics applied to large-scale neuropeptide identification
title_full Analytic framework for peptidomics applied to large-scale neuropeptide identification
title_fullStr Analytic framework for peptidomics applied to large-scale neuropeptide identification
title_full_unstemmed Analytic framework for peptidomics applied to large-scale neuropeptide identification
title_sort analytic framework for peptidomics applied to large-scale neuropeptide identification
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/3c5d7d3bb3cc41ce8dc8f62c4a6c9d28
work_keys_str_mv AT annasecher analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification
AT christiandkelstrup analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification
AT kilianwcondefrieboes analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification
AT charlespyke analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification
AT kirstenraun analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification
AT birgitteswulff analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification
AT jespervolsen analyticframeworkforpeptidomicsappliedtolargescaleneuropeptideidentification
_version_ 1718380242197807104