Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma

Waldo Loayza-Gamboa,1,2 Vladimir Martel-Ramirez,1,3 Vanessa Inga-Condezo,1,3 Vanessa Valderrama-Albino,2,3 Rosa Alvarado-Villacorta,2,3 Diego Valera-Cornejo2,3 1Glaucoma Department, Instituto Nacional de Oftalmología “Francisco Contreras Campos”, Lima, Perú;...

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Autores principales:	Loayza-Gamboa W, Martel-Ramirez V, Inga-Condezo V, Valderrama-Albino V, Alvarado-Villacorta R, Valera-Cornejo D
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	glaucoma surgery cataract surgery gonioscopy-assisted trabeculotomy ab interno transluminal Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3c5f765a24544ad9af156b4a9ad8eb89
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spelling	oai:doaj.org-article:3c5f765a24544ad9af156b4a9ad8eb892021-12-02T11:15:22ZOutcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma1177-5483https://doaj.org/article/3c5f765a24544ad9af156b4a9ad8eb892020-10-01T00:00:00Zhttps://www.dovepress.com/outcomes-of-combined-prolene-gonioscopy-assisted-transluminal-trabecul-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Waldo Loayza-Gamboa,1,2 Vladimir Martel-Ramirez,1,3 Vanessa Inga-Condezo,1,3 Vanessa Valderrama-Albino,2,3 Rosa Alvarado-Villacorta,2,3 Diego Valera-Cornejo2,3 1Glaucoma Department, Instituto Nacional de Oftalmología “Francisco Contreras Campos”, Lima, Perú; 2Research unit, Clínica Vista, Lima, Perú; 3Faculty of medicine, Universidad Peruana Cayetano Heredia, Lima, PeruCorrespondence: Diego Valera-CornejoVista Clinic, Jirón Caracas 2410 Jesús María, Lima, PerúTel +51 1 6413217Email diegoavalera@gmail.comPurpose: To describe the clinical outcomes of combined prolene gonioscopy assisted transluminal trabeculotomy (GATT) with phacoemulsification in patients with open-angle glaucoma.Methods: Retrospective study of patients with cataract and open-angle glaucoma treated with GATT and phacoemulsification with intraocular lens (IOL) implantation. Patients with neovascular glaucoma, corneal decompensation, unstable IOL, and with bleeding disorders were excluded. The cumulative probability of failure was the primary outcome. Secondary outcomes were the complete success rate, the mean change on intraocular pressure (IOP), best-corrected visual acuity (BCVA) and number of glaucoma medications at the last follow-up. The frequency of complications was also recorded.Results: Thirty two eyes (25 patients) were included. Nineteen (59.3%) were females, with a mean age of 73.4± 12.4 (23– 87 years) and a mean baseline BCVA of 1.1± 0.75 (0.3– 3) LogMAR units. The cumulative probability of failure was 3.2% at 1 month and 6.3% at 6 and 12 months. Sixty-eight and 65.5% of eyes achieved complete success at 3 and 6 months, respectively. The reduction of IOP and number of glaucoma medications at 6 months were statistically significant (p< 0.0001 and p=0.0002, respectively). There was a statistically significant improvement of BCVA (from 1.1± 0.7 to 0.4± 0.7) at 6 months (p< 0.0001). IOP spikes (18.7%) and transient hyphema (9.3%) were the most common complications.Conclusion: Combined GATT with cataract surgery reduced the IOP and was associated with low failure rates and few ocular complications. This procedure offers the advantage to avoid the need for a bleb, scleral, or conjunctival incision, allowing the possibility for future glaucoma procedures.Keywords: glaucoma surgery, cataract surgery, Gonioscopy-assisted, trabeculotomy, ab interno, transluminalLoayza-Gamboa WMartel-Ramirez VInga-Condezo VValderrama-Albino VAlvarado-Villacorta RValera-Cornejo DDove Medical Pressarticleglaucoma surgerycataract surgerygonioscopy-assistedtrabeculotomyab internotransluminalOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 3009-3016 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	glaucoma surgery cataract surgery gonioscopy-assisted trabeculotomy ab interno transluminal Ophthalmology RE1-994
spellingShingle	glaucoma surgery cataract surgery gonioscopy-assisted trabeculotomy ab interno transluminal Ophthalmology RE1-994 Loayza-Gamboa W Martel-Ramirez V Inga-Condezo V Valderrama-Albino V Alvarado-Villacorta R Valera-Cornejo D Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma
description	Waldo Loayza-Gamboa,1,2 Vladimir Martel-Ramirez,1,3 Vanessa Inga-Condezo,1,3 Vanessa Valderrama-Albino,2,3 Rosa Alvarado-Villacorta,2,3 Diego Valera-Cornejo2,3 1Glaucoma Department, Instituto Nacional de Oftalmología “Francisco Contreras Campos”, Lima, Perú; 2Research unit, Clínica Vista, Lima, Perú; 3Faculty of medicine, Universidad Peruana Cayetano Heredia, Lima, PeruCorrespondence: Diego Valera-CornejoVista Clinic, Jirón Caracas 2410 Jesús María, Lima, PerúTel +51 1 6413217Email diegoavalera@gmail.comPurpose: To describe the clinical outcomes of combined prolene gonioscopy assisted transluminal trabeculotomy (GATT) with phacoemulsification in patients with open-angle glaucoma.Methods: Retrospective study of patients with cataract and open-angle glaucoma treated with GATT and phacoemulsification with intraocular lens (IOL) implantation. Patients with neovascular glaucoma, corneal decompensation, unstable IOL, and with bleeding disorders were excluded. The cumulative probability of failure was the primary outcome. Secondary outcomes were the complete success rate, the mean change on intraocular pressure (IOP), best-corrected visual acuity (BCVA) and number of glaucoma medications at the last follow-up. The frequency of complications was also recorded.Results: Thirty two eyes (25 patients) were included. Nineteen (59.3%) were females, with a mean age of 73.4± 12.4 (23– 87 years) and a mean baseline BCVA of 1.1± 0.75 (0.3– 3) LogMAR units. The cumulative probability of failure was 3.2% at 1 month and 6.3% at 6 and 12 months. Sixty-eight and 65.5% of eyes achieved complete success at 3 and 6 months, respectively. The reduction of IOP and number of glaucoma medications at 6 months were statistically significant (p< 0.0001 and p=0.0002, respectively). There was a statistically significant improvement of BCVA (from 1.1± 0.7 to 0.4± 0.7) at 6 months (p< 0.0001). IOP spikes (18.7%) and transient hyphema (9.3%) were the most common complications.Conclusion: Combined GATT with cataract surgery reduced the IOP and was associated with low failure rates and few ocular complications. This procedure offers the advantage to avoid the need for a bleb, scleral, or conjunctival incision, allowing the possibility for future glaucoma procedures.Keywords: glaucoma surgery, cataract surgery, Gonioscopy-assisted, trabeculotomy, ab interno, transluminal
format	article
author	Loayza-Gamboa W Martel-Ramirez V Inga-Condezo V Valderrama-Albino V Alvarado-Villacorta R Valera-Cornejo D
author_facet	Loayza-Gamboa W Martel-Ramirez V Inga-Condezo V Valderrama-Albino V Alvarado-Villacorta R Valera-Cornejo D
author_sort	Loayza-Gamboa W
title	Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma
title_short	Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma
title_full	Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma
title_fullStr	Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma
title_full_unstemmed	Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma
title_sort	outcomes of combined prolene gonioscopy assisted transluminal trabeculotomy with phacoemulsification in open-angle glaucoma
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/3c5f765a24544ad9af156b4a9ad8eb89
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Outcomes of Combined Prolene Gonioscopy Assisted Transluminal Trabeculotomy with Phacoemulsification in Open-Angle Glaucoma

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