Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades

The neural mechanisms by which the brain initiates self-generated actions are unclear. The authors show, using population imaging and single-cell ablation, that ramp-to-threshold firing dynamics over multiple seconds is critical for the initiation of self-generated eye movements.

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Autores principales: Alexandro D. Ramirez, Emre R. F. Aksay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3c63831134af47e5959a4f77b35d538e
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spelling oai:doaj.org-article:3c63831134af47e5959a4f77b35d538e2021-12-02T18:33:59ZRamp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades10.1038/s41467-021-24336-w2041-1723https://doaj.org/article/3c63831134af47e5959a4f77b35d538e2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24336-whttps://doaj.org/toc/2041-1723The neural mechanisms by which the brain initiates self-generated actions are unclear. The authors show, using population imaging and single-cell ablation, that ramp-to-threshold firing dynamics over multiple seconds is critical for the initiation of self-generated eye movements.Alexandro D. RamirezEmre R. F. AksayNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexandro D. Ramirez
Emre R. F. Aksay
Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
description The neural mechanisms by which the brain initiates self-generated actions are unclear. The authors show, using population imaging and single-cell ablation, that ramp-to-threshold firing dynamics over multiple seconds is critical for the initiation of self-generated eye movements.
format article
author Alexandro D. Ramirez
Emre R. F. Aksay
author_facet Alexandro D. Ramirez
Emre R. F. Aksay
author_sort Alexandro D. Ramirez
title Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
title_short Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
title_full Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
title_fullStr Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
title_full_unstemmed Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
title_sort ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/3c63831134af47e5959a4f77b35d538e
work_keys_str_mv AT alexandrodramirez ramptothresholddynamicsinahindbrainpopulationcontrolsthetimingofspontaneoussaccades
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