Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades
The neural mechanisms by which the brain initiates self-generated actions are unclear. The authors show, using population imaging and single-cell ablation, that ramp-to-threshold firing dynamics over multiple seconds is critical for the initiation of self-generated eye movements.
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Nature Portfolio
2021
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oai:doaj.org-article:3c63831134af47e5959a4f77b35d538e2021-12-02T18:33:59ZRamp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades10.1038/s41467-021-24336-w2041-1723https://doaj.org/article/3c63831134af47e5959a4f77b35d538e2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24336-whttps://doaj.org/toc/2041-1723The neural mechanisms by which the brain initiates self-generated actions are unclear. The authors show, using population imaging and single-cell ablation, that ramp-to-threshold firing dynamics over multiple seconds is critical for the initiation of self-generated eye movements.Alexandro D. RamirezEmre R. F. AksayNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021) |
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Science Q Alexandro D. Ramirez Emre R. F. Aksay Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades |
description |
The neural mechanisms by which the brain initiates self-generated actions are unclear. The authors show, using population imaging and single-cell ablation, that ramp-to-threshold firing dynamics over multiple seconds is critical for the initiation of self-generated eye movements. |
format |
article |
author |
Alexandro D. Ramirez Emre R. F. Aksay |
author_facet |
Alexandro D. Ramirez Emre R. F. Aksay |
author_sort |
Alexandro D. Ramirez |
title |
Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades |
title_short |
Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades |
title_full |
Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades |
title_fullStr |
Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades |
title_full_unstemmed |
Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades |
title_sort |
ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/3c63831134af47e5959a4f77b35d538e |
work_keys_str_mv |
AT alexandrodramirez ramptothresholddynamicsinahindbrainpopulationcontrolsthetimingofspontaneoussaccades AT emrerfaksay ramptothresholddynamicsinahindbrainpopulationcontrolsthetimingofspontaneoussaccades |
_version_ |
1718377913730990080 |