Tunable genetic devices through simultaneous control of transcription and translation

Synthetic genetic circuits are sensitive to their environment and host cell, requiring many rounds of physical reassembly to achieve a desired function. Here the authors use a multi-level regulatory motif to dynamically tune the function of genetic parts as a step towards robust adaptive circuits.

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Bibliographic Details
Main Authors: Vittorio Bartoli, Grace A. Meaker, Mario di Bernardo, Thomas E. Gorochowski
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/3c64e96ed5e9493bac7f1b5bff3219ee
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