NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
The use of immunotherapy can be limited by adverse side effects. In this study, the authors designed a nanodevice that spatiotemporally controlled activate immunomodulatory agents at the tumour site upon near-infrared light triggering, thus preventing systemic toxicity with maintained efficacy
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Nature Portfolio
2019
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oai:doaj.org-article:3c67c3eabb524d83b45e5b60841e08d92021-12-02T14:39:18ZNIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices10.1038/s41467-019-10847-02041-1723https://doaj.org/article/3c67c3eabb524d83b45e5b60841e08d92019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10847-0https://doaj.org/toc/2041-1723The use of immunotherapy can be limited by adverse side effects. In this study, the authors designed a nanodevice that spatiotemporally controlled activate immunomodulatory agents at the tumour site upon near-infrared light triggering, thus preventing systemic toxicity with maintained efficacyHongqian ChuJian ZhaoYongsheng MiZhenghan DiLele LiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Hongqian Chu Jian Zhao Yongsheng Mi Zhenghan Di Lele Li NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices |
description |
The use of immunotherapy can be limited by adverse side effects. In this study, the authors designed a nanodevice that spatiotemporally controlled activate immunomodulatory agents at the tumour site upon near-infrared light triggering, thus preventing systemic toxicity with maintained efficacy |
format |
article |
author |
Hongqian Chu Jian Zhao Yongsheng Mi Zhenghan Di Lele Li |
author_facet |
Hongqian Chu Jian Zhao Yongsheng Mi Zhenghan Di Lele Li |
author_sort |
Hongqian Chu |
title |
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices |
title_short |
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices |
title_full |
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices |
title_fullStr |
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices |
title_full_unstemmed |
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices |
title_sort |
nir-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/3c67c3eabb524d83b45e5b60841e08d9 |
work_keys_str_mv |
AT hongqianchu nirlightmediatedspatiallyselectivetriggeringofantitumorimmunityviaupconversionnanoparticlebasedimmunodevices AT jianzhao nirlightmediatedspatiallyselectivetriggeringofantitumorimmunityviaupconversionnanoparticlebasedimmunodevices AT yongshengmi nirlightmediatedspatiallyselectivetriggeringofantitumorimmunityviaupconversionnanoparticlebasedimmunodevices AT zhenghandi nirlightmediatedspatiallyselectivetriggeringofantitumorimmunityviaupconversionnanoparticlebasedimmunodevices AT leleli nirlightmediatedspatiallyselectivetriggeringofantitumorimmunityviaupconversionnanoparticlebasedimmunodevices |
_version_ |
1718390650042318848 |