NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices

The use of immunotherapy can be limited by adverse side effects. In this study, the authors designed a nanodevice that spatiotemporally controlled activate immunomodulatory agents at the tumour site upon near-infrared light triggering, thus preventing systemic toxicity with maintained efficacy

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Autores principales: Hongqian Chu, Jian Zhao, Yongsheng Mi, Zhenghan Di, Lele Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3c67c3eabb524d83b45e5b60841e08d9
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spelling oai:doaj.org-article:3c67c3eabb524d83b45e5b60841e08d92021-12-02T14:39:18ZNIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices10.1038/s41467-019-10847-02041-1723https://doaj.org/article/3c67c3eabb524d83b45e5b60841e08d92019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10847-0https://doaj.org/toc/2041-1723The use of immunotherapy can be limited by adverse side effects. In this study, the authors designed a nanodevice that spatiotemporally controlled activate immunomodulatory agents at the tumour site upon near-infrared light triggering, thus preventing systemic toxicity with maintained efficacyHongqian ChuJian ZhaoYongsheng MiZhenghan DiLele LiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hongqian Chu
Jian Zhao
Yongsheng Mi
Zhenghan Di
Lele Li
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
description The use of immunotherapy can be limited by adverse side effects. In this study, the authors designed a nanodevice that spatiotemporally controlled activate immunomodulatory agents at the tumour site upon near-infrared light triggering, thus preventing systemic toxicity with maintained efficacy
format article
author Hongqian Chu
Jian Zhao
Yongsheng Mi
Zhenghan Di
Lele Li
author_facet Hongqian Chu
Jian Zhao
Yongsheng Mi
Zhenghan Di
Lele Li
author_sort Hongqian Chu
title NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
title_short NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
title_full NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
title_fullStr NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
title_full_unstemmed NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
title_sort nir-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3c67c3eabb524d83b45e5b60841e08d9
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AT yongshengmi nirlightmediatedspatiallyselectivetriggeringofantitumorimmunityviaupconversionnanoparticlebasedimmunodevices
AT zhenghandi nirlightmediatedspatiallyselectivetriggeringofantitumorimmunityviaupconversionnanoparticlebasedimmunodevices
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