Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface

Streptococcus pneumoniae is a common coloniser of the human nasopharynx, but it also causes severe diseases. Here, Weight et al. use an experimental human pneumococcal carriage model to show that bacterial colonisation is associated with invasion of the epithelium and enhancement of immune responses...

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Autores principales:	Caroline M. Weight, Cristina Venturini, Sherin Pojar, Simon P. Jochems, Jesús Reiné, Elissavet Nikolaou, Carla Solórzano, Mahdad Noursadeghi, Jeremy S. Brown, Daniela M. Ferreira, Robert S. Heyderman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3c6930e347864574b60eb273783446c3
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spelling	oai:doaj.org-article:3c6930e347864574b60eb273783446c32021-12-02T15:35:47ZMicroinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface10.1038/s41467-019-11005-22041-1723https://doaj.org/article/3c6930e347864574b60eb273783446c32019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11005-2https://doaj.org/toc/2041-1723Streptococcus pneumoniae is a common coloniser of the human nasopharynx, but it also causes severe diseases. Here, Weight et al. use an experimental human pneumococcal carriage model to show that bacterial colonisation is associated with invasion of the epithelium and enhancement of immune responses.Caroline M. WeightCristina VenturiniSherin PojarSimon P. JochemsJesús ReinéElissavet NikolaouCarla SolórzanoMahdad NoursadeghiJeremy S. BrownDaniela M. FerreiraRobert S. HeydermanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Caroline M. Weight Cristina Venturini Sherin Pojar Simon P. Jochems Jesús Reiné Elissavet Nikolaou Carla Solórzano Mahdad Noursadeghi Jeremy S. Brown Daniela M. Ferreira Robert S. Heyderman Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
description	Streptococcus pneumoniae is a common coloniser of the human nasopharynx, but it also causes severe diseases. Here, Weight et al. use an experimental human pneumococcal carriage model to show that bacterial colonisation is associated with invasion of the epithelium and enhancement of immune responses.
format	article
author	Caroline M. Weight Cristina Venturini Sherin Pojar Simon P. Jochems Jesús Reiné Elissavet Nikolaou Carla Solórzano Mahdad Noursadeghi Jeremy S. Brown Daniela M. Ferreira Robert S. Heyderman
author_facet	Caroline M. Weight Cristina Venturini Sherin Pojar Simon P. Jochems Jesús Reiné Elissavet Nikolaou Carla Solórzano Mahdad Noursadeghi Jeremy S. Brown Daniela M. Ferreira Robert S. Heyderman
author_sort	Caroline M. Weight
title	Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
title_short	Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
title_full	Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
title_fullStr	Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
title_full_unstemmed	Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
title_sort	microinvasion by streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3c6930e347864574b60eb273783446c3
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Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface

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