An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine

Identifying readers of epigenetic marks is a critical step for understanding the role of epigenetic marks in biology. Here, the authors applied DAPPL, an all-to-all approach to profile the interactions between TFs and epigenetic modified DNA libraries.

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Detalles Bibliográficos
Autores principales: Guang Song, Guohua Wang, Ximei Luo, Ying Cheng, Qifeng Song, Jun Wan, Cedric Moore, Hongjun Song, Peng Jin, Jiang Qian, Heng Zhu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3c6c0bb7285349ad8d538d0be72b8dfe
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Sumario:Identifying readers of epigenetic marks is a critical step for understanding the role of epigenetic marks in biology. Here, the authors applied DAPPL, an all-to-all approach to profile the interactions between TFs and epigenetic modified DNA libraries.