Regulation of monocyte cell fate by blood vessels mediated by Notch signalling
Circulating Ly6Clo monocytes are thought to be derived from Ly6Chi subset. Here the authors show that Notch signalling is activated in Ly6Clocells and is required for their differentiation, and that Notch ligands that initiate this signalling are provided by a subset of endothelial cells.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/3c7171e198e9430da0d78f693f4209d9 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:3c7171e198e9430da0d78f693f4209d9 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:3c7171e198e9430da0d78f693f4209d92021-12-02T17:32:20ZRegulation of monocyte cell fate by blood vessels mediated by Notch signalling10.1038/ncomms125972041-1723https://doaj.org/article/3c7171e198e9430da0d78f693f4209d92016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12597https://doaj.org/toc/2041-1723Circulating Ly6Clo monocytes are thought to be derived from Ly6Chi subset. Here the authors show that Notch signalling is activated in Ly6Clocells and is required for their differentiation, and that Notch ligands that initiate this signalling are provided by a subset of endothelial cells.Jaba GamrekelashviliRoberto GiagnorioJasmin JussofieOliver SoehnleinJohan DucheneCarlos G. BriseñoSaravana K. RamasamyKashyap KrishnasamyAnne LimbourgChristine HägerTamar KapanadzeChieko IshifuneRabea HinkelFreddy RadtkeLothar J. StroblUrsula Zimber-StroblL. Christian NappJohann BauersachsHermann HallerKoji YasutomoChristian KupattKenneth M. MurphyRalf H. AdamsChristian WeberFlorian P. LimbourgNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jaba Gamrekelashvili Roberto Giagnorio Jasmin Jussofie Oliver Soehnlein Johan Duchene Carlos G. Briseño Saravana K. Ramasamy Kashyap Krishnasamy Anne Limbourg Christine Häger Tamar Kapanadze Chieko Ishifune Rabea Hinkel Freddy Radtke Lothar J. Strobl Ursula Zimber-Strobl L. Christian Napp Johann Bauersachs Hermann Haller Koji Yasutomo Christian Kupatt Kenneth M. Murphy Ralf H. Adams Christian Weber Florian P. Limbourg Regulation of monocyte cell fate by blood vessels mediated by Notch signalling |
| description |
Circulating Ly6Clo monocytes are thought to be derived from Ly6Chi subset. Here the authors show that Notch signalling is activated in Ly6Clocells and is required for their differentiation, and that Notch ligands that initiate this signalling are provided by a subset of endothelial cells. |
| format |
article |
| author |
Jaba Gamrekelashvili Roberto Giagnorio Jasmin Jussofie Oliver Soehnlein Johan Duchene Carlos G. Briseño Saravana K. Ramasamy Kashyap Krishnasamy Anne Limbourg Christine Häger Tamar Kapanadze Chieko Ishifune Rabea Hinkel Freddy Radtke Lothar J. Strobl Ursula Zimber-Strobl L. Christian Napp Johann Bauersachs Hermann Haller Koji Yasutomo Christian Kupatt Kenneth M. Murphy Ralf H. Adams Christian Weber Florian P. Limbourg |
| author_facet |
Jaba Gamrekelashvili Roberto Giagnorio Jasmin Jussofie Oliver Soehnlein Johan Duchene Carlos G. Briseño Saravana K. Ramasamy Kashyap Krishnasamy Anne Limbourg Christine Häger Tamar Kapanadze Chieko Ishifune Rabea Hinkel Freddy Radtke Lothar J. Strobl Ursula Zimber-Strobl L. Christian Napp Johann Bauersachs Hermann Haller Koji Yasutomo Christian Kupatt Kenneth M. Murphy Ralf H. Adams Christian Weber Florian P. Limbourg |
| author_sort |
Jaba Gamrekelashvili |
| title |
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling |
| title_short |
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling |
| title_full |
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling |
| title_fullStr |
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling |
| title_full_unstemmed |
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling |
| title_sort |
regulation of monocyte cell fate by blood vessels mediated by notch signalling |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/3c7171e198e9430da0d78f693f4209d9 |
| work_keys_str_mv |
AT jabagamrekelashvili regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT robertogiagnorio regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT jasminjussofie regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT oliversoehnlein regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT johanduchene regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT carlosgbriseno regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT saravanakramasamy regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT kashyapkrishnasamy regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT annelimbourg regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT christinehager regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT tamarkapanadze regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT chiekoishifune regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT rabeahinkel regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT freddyradtke regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT lotharjstrobl regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT ursulazimberstrobl regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT lchristiannapp regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT johannbauersachs regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT hermannhaller regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT kojiyasutomo regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT christiankupatt regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT kennethmmurphy regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT ralfhadams regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT christianweber regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling AT florianplimbourg regulationofmonocytecellfatebybloodvesselsmediatedbynotchsignalling |
| _version_ |
1718380303776481280 |