Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins

Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response. In this study, we investigate the mechanism of action of the MARCH family of cellular proteins...

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Autores principales:	Cheng Man Lun, Abdul A. Waheed, Ahlam Majadly, Nicole Powell, Eric O. Freed
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/3c7a61ed474c4f8eb8ac2adcfc05c411
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spelling	oai:doaj.org-article:3c7a61ed474c4f8eb8ac2adcfc05c4112021-11-03T18:56:09ZMechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins2150-751110.1128/mBio.00219-21https://doaj.org/article/3c7a61ed474c4f8eb8ac2adcfc05c4112021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00219-21https://doaj.org/toc/2150-7511 Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response. In this study, we investigate the mechanism of action of the MARCH family of cellular proteins that disrupt the trafficking and virion incorporation of viral glycoproteins across several virus families.Cheng Man LunAbdul A. WaheedAhlam MajadlyNicole PowellEric O. FreedAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Cheng Man Lun Abdul A. Waheed Ahlam Majadly Nicole Powell Eric O. Freed Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
description	Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response. In this study, we investigate the mechanism of action of the MARCH family of cellular proteins that disrupt the trafficking and virion incorporation of viral glycoproteins across several virus families.
format	article
author	Cheng Man Lun Abdul A. Waheed Ahlam Majadly Nicole Powell Eric O. Freed
author_facet	Cheng Man Lun Abdul A. Waheed Ahlam Majadly Nicole Powell Eric O. Freed
author_sort	Cheng Man Lun
title	Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
title_short	Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
title_full	Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
title_fullStr	Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
title_full_unstemmed	Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
title_sort	mechanism of viral glycoprotein targeting by membrane-associated ring-ch proteins
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/3c7a61ed474c4f8eb8ac2adcfc05c411
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Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins

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