EP4 inhibition attenuates the development of diabetic and non-diabetic experimental kidney disease

EP4 inhibition attenuates the development of diabetic and non-diabetic experimental kidney disease

Abstract The therapeutic targeting of prostanoid subtype receptors may slow the development of chronic kidney disease (CKD) through mechanisms that are distinct from those of upstream COX inhibition. Here, employing multiple experimental models of CKD, we studied the effects of inhibition of the EP4...

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Main Authors: Karina Thieme, Syamantak Majumder, Angela S. Brijmohan, Sri N. Batchu, Bridgit B. Bowskill, Tamadher A. Alghamdi, Suzanne L. Advani, M. Golam Kabir, Youan Liu, Andrew Advani
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/3c7f7c6c5c3f478c808baefc6898c731
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