Compositional Characteristics of Glucuronide Conjugates in Regional Glechoma hederacea var. longituba Herbal Extracts Using a Set of Polyphenolic Marker Compounds

Glechoma hederacea var. longituba (GHL) is one of many herbal plants widely used in hot herbal teas and in oriental prescriptions to treat various diseases. Although the beneficial effects of GHL may be influenced by differences in the composition of active cons...

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Autores principales:	Young Hye Hahm, Kun Cho, Yeong Hee Ahn
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Glechoma hederacea</i> var. <i>longituba</i> polyphenol glucuronide conjugate compositional characteristics LC–mass spectrometry Botany QK1-989
Acceso en línea:	https://doaj.org/article/3c8de69832804cfd8934b153e418e1d8
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spelling	oai:doaj.org-article:3c8de69832804cfd8934b153e418e1d82021-11-25T18:45:42ZCompositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds10.3390/plants101123532223-7747https://doaj.org/article/3c8de69832804cfd8934b153e418e1d82021-10-01T00:00:00Zhttps://www.mdpi.com/2223-7747/10/11/2353https://doaj.org/toc/2223-7747<i>Glechoma hederacea</i> var. <i>longituba</i> (GHL) is one of many herbal plants widely used in hot herbal teas and in oriental prescriptions to treat various diseases. Although the beneficial effects of GHL may be influenced by differences in the composition of active constituents in the herbal extracts, there are few reports on the compositional characteristics of GHL herbal extracts to date. In this study, liquid chromatography–mass spectrometry technology was used for comparative analysis of constituents in hot-water extracts of GHL samples obtained from various cultivating provinces in South Korea. A set of marker panel consisting of nine polyphenolic compounds, including glucuronide conjugates in particular, was constructed and used to monitor the compositional characteristics in each GHL extract. Our findings show that some of the marker compounds, including rosmarinic acid, were persistently observed as major constituents in the analyses of the 22 GHL sample extracts, whereas, interestingly, other marker compounds such as polyphenol-glucuronic acid conjugates displayed dramatic differences in compositional ratios. This chromatographic approach using the marker compound panel can be applied to qualitatively and quantitatively evaluate compositional characteristics in the GHL extracts, and can also be useful for quality assays of the GHL herbal plant in medicinal and industrial fields.Young Hye HahmKun ChoYeong Hee AhnMDPI AGarticle<i>Glechoma hederacea</i> var. <i>longituba</i>polyphenolglucuronide conjugatecompositional characteristicsLC–mass spectrometryBotanyQK1-989ENPlants, Vol 10, Iss 2353, p 2353 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Glechoma hederacea</i> var. <i>longituba</i> polyphenol glucuronide conjugate compositional characteristics LC–mass spectrometry Botany QK1-989
spellingShingle	<i>Glechoma hederacea</i> var. <i>longituba</i> polyphenol glucuronide conjugate compositional characteristics LC–mass spectrometry Botany QK1-989 Young Hye Hahm Kun Cho Yeong Hee Ahn Compositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds
description	<i>Glechoma hederacea</i> var. <i>longituba</i> (GHL) is one of many herbal plants widely used in hot herbal teas and in oriental prescriptions to treat various diseases. Although the beneficial effects of GHL may be influenced by differences in the composition of active constituents in the herbal extracts, there are few reports on the compositional characteristics of GHL herbal extracts to date. In this study, liquid chromatography–mass spectrometry technology was used for comparative analysis of constituents in hot-water extracts of GHL samples obtained from various cultivating provinces in South Korea. A set of marker panel consisting of nine polyphenolic compounds, including glucuronide conjugates in particular, was constructed and used to monitor the compositional characteristics in each GHL extract. Our findings show that some of the marker compounds, including rosmarinic acid, were persistently observed as major constituents in the analyses of the 22 GHL sample extracts, whereas, interestingly, other marker compounds such as polyphenol-glucuronic acid conjugates displayed dramatic differences in compositional ratios. This chromatographic approach using the marker compound panel can be applied to qualitatively and quantitatively evaluate compositional characteristics in the GHL extracts, and can also be useful for quality assays of the GHL herbal plant in medicinal and industrial fields.
format	article
author	Young Hye Hahm Kun Cho Yeong Hee Ahn
author_facet	Young Hye Hahm Kun Cho Yeong Hee Ahn
author_sort	Young Hye Hahm
title	Compositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds
title_short	Compositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds
title_full	Compositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds
title_fullStr	Compositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds
title_full_unstemmed	Compositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds
title_sort	compositional characteristics of glucuronide conjugates in regional <i>glechoma hederacea</i> var. <i>longituba</i> herbal extracts using a set of polyphenolic marker compounds
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/3c8de69832804cfd8934b153e418e1d8
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Compositional Characteristics of Glucuronide Conjugates in Regional <i>Glechoma hederacea</i> var. <i>longituba</i> Herbal Extracts Using a Set of Polyphenolic Marker Compounds

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