Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials

Patrick Oellers,1,2 Dilraj S Grewal,1,2 Sharon Fekrat1,2 1Duke Eye Center, Duke University Medical Center, 2Surgical Service, Durham Veterans Affairs Medical Center, Durham, NC, USA Abstract: For years, the standard of care for branch-retinal-vein-occlusion-associated macular edema was initial obs...

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Autores principales: Oellers P, Grewal DS, Fekrat S
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Publicado: Dove Medical Press 2016
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Acceso en línea:https://doaj.org/article/3c92590f7ceb47eeadd0763d90e059b6
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spelling oai:doaj.org-article:3c92590f7ceb47eeadd0763d90e059b62021-12-02T02:27:51ZRole of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials1177-5483https://doaj.org/article/3c92590f7ceb47eeadd0763d90e059b62016-03-01T00:00:00Zhttps://www.dovepress.com/role-of-aflibercept-for-macular-edema-following-branch-retinal-vein-oc-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Patrick Oellers,1,2 Dilraj S Grewal,1,2 Sharon Fekrat1,2 1Duke Eye Center, Duke University Medical Center, 2Surgical Service, Durham Veterans Affairs Medical Center, Durham, NC, USA Abstract: For years, the standard of care for branch-retinal-vein-occlusion-associated macular edema was initial observation followed by grid-pattern laser photocoagulation for persistent edema. Newer pharmacologic options have revolutionized the management of branch-retinal-vein-occlusion-associated macular edema, and the visual outcomes of these eyes are better than ever. However, a variety of available treatment options including intravitreal corticosteroids and intravitreal anti-vascular endothelial growth factor agents have established novel challenges with regard to appropriate drug selection. This review summarizes the available clinical studies with special emphasis on the comparison of intravitreal aflibercept with ranibizumab, bevacizumab, and steroid agents. Keywords: branch retinal vein occlusion, BRVO, macular edema, cystoid macular edema, grid-pattern laser photocoagulation, triamcinolone, dexamethasone implant, ranibizumab, bevacizumab, pegaptanib, anti-vascular endothelial growth factorOellers PGrewal DSFekrat SDove Medical Pressarticlebranch retinal vein occlusionBRVOmacular edemacystoid macularOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 411-418 (2016)
institution DOAJ
collection DOAJ
language EN
topic branch retinal vein occlusion
BRVO
macular edema
cystoid macular
Ophthalmology
RE1-994
spellingShingle branch retinal vein occlusion
BRVO
macular edema
cystoid macular
Ophthalmology
RE1-994
Oellers P
Grewal DS
Fekrat S
Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials
description Patrick Oellers,1,2 Dilraj S Grewal,1,2 Sharon Fekrat1,2 1Duke Eye Center, Duke University Medical Center, 2Surgical Service, Durham Veterans Affairs Medical Center, Durham, NC, USA Abstract: For years, the standard of care for branch-retinal-vein-occlusion-associated macular edema was initial observation followed by grid-pattern laser photocoagulation for persistent edema. Newer pharmacologic options have revolutionized the management of branch-retinal-vein-occlusion-associated macular edema, and the visual outcomes of these eyes are better than ever. However, a variety of available treatment options including intravitreal corticosteroids and intravitreal anti-vascular endothelial growth factor agents have established novel challenges with regard to appropriate drug selection. This review summarizes the available clinical studies with special emphasis on the comparison of intravitreal aflibercept with ranibizumab, bevacizumab, and steroid agents. Keywords: branch retinal vein occlusion, BRVO, macular edema, cystoid macular edema, grid-pattern laser photocoagulation, triamcinolone, dexamethasone implant, ranibizumab, bevacizumab, pegaptanib, anti-vascular endothelial growth factor
format article
author Oellers P
Grewal DS
Fekrat S
author_facet Oellers P
Grewal DS
Fekrat S
author_sort Oellers P
title Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials
title_short Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials
title_full Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials
title_fullStr Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials
title_full_unstemmed Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials
title_sort role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/3c92590f7ceb47eeadd0763d90e059b6
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AT fekrats roleofafliberceptformacularedemafollowingbranchretinalveinocclusioncomparisonofclinicaltrials
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