Optimal breast cancer screening strategies for older women: current perspectives

Dejana Braithwaite,1 Joshua Demb,1 Louise M Henderson2 1Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, 2Department of Radiology, University of North Carolina, Chapel Hill, NC, USA Abstract: Breast cancer is a major cause of cancer-related deaths among ol...

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Autores principales:	Braithwaite D, Demb J, Henderson LM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	older women breast cancer screening mammography Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/3c968c5f54194b1bafe3ecad2d2ff57e
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spelling	oai:doaj.org-article:3c968c5f54194b1bafe3ecad2d2ff57e2021-12-02T06:03:32ZOptimal breast cancer screening strategies for older women: current perspectives1178-1998https://doaj.org/article/3c968c5f54194b1bafe3ecad2d2ff57e2016-02-01T00:00:00Zhttps://www.dovepress.com/optimal-breast-cancer-screening-strategies-for-older-women-current-per-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Dejana Braithwaite,1 Joshua Demb,1 Louise M Henderson2 1Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, 2Department of Radiology, University of North Carolina, Chapel Hill, NC, USA Abstract: Breast cancer is a major cause of cancer-related deaths among older women, aged 65 years or older. Screening mammography has been shown to be effective in reducing breast cancer mortality in women aged 50–74 years but not among those aged 75 years or older. Given the large heterogeneity in comorbidity status and life expectancy among older women, controversy remains over screening mammography in this population. Diminished life expectancy with aging may decrease the potential screening benefit and increase the risk of harms. In this review, we summarize the evidence on screening mammography utilization, performance, and outcomes and highlight evidence gaps. Optimizing the screening strategy will involve separating older women who will benefit from screening from those who will not benefit by using information on comorbidity status and life expectancy. This review has identified areas related to screening mammography in older women that warrant additional research, including the need to evaluate emerging screening technologies, such as tomosynthesis among older women and precision cancer screening. In the absence of randomized controlled trials, the benefits and harms of continued screening mammography in older women need to be estimated using both population-based cohort data and simulation models. Keywords: aging, breast cancer, precision cancer screeningBraithwaite DDemb JHenderson LMDove Medical Pressarticleolder womenbreast cancerscreening mammographyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 11, Pp 111-125 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	older women breast cancer screening mammography Geriatrics RC952-954.6
spellingShingle	older women breast cancer screening mammography Geriatrics RC952-954.6 Braithwaite D Demb J Henderson LM Optimal breast cancer screening strategies for older women: current perspectives
description	Dejana Braithwaite,1 Joshua Demb,1 Louise M Henderson2 1Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, 2Department of Radiology, University of North Carolina, Chapel Hill, NC, USA Abstract: Breast cancer is a major cause of cancer-related deaths among older women, aged 65 years or older. Screening mammography has been shown to be effective in reducing breast cancer mortality in women aged 50–74 years but not among those aged 75 years or older. Given the large heterogeneity in comorbidity status and life expectancy among older women, controversy remains over screening mammography in this population. Diminished life expectancy with aging may decrease the potential screening benefit and increase the risk of harms. In this review, we summarize the evidence on screening mammography utilization, performance, and outcomes and highlight evidence gaps. Optimizing the screening strategy will involve separating older women who will benefit from screening from those who will not benefit by using information on comorbidity status and life expectancy. This review has identified areas related to screening mammography in older women that warrant additional research, including the need to evaluate emerging screening technologies, such as tomosynthesis among older women and precision cancer screening. In the absence of randomized controlled trials, the benefits and harms of continued screening mammography in older women need to be estimated using both population-based cohort data and simulation models. Keywords: aging, breast cancer, precision cancer screening
format	article
author	Braithwaite D Demb J Henderson LM
author_facet	Braithwaite D Demb J Henderson LM
author_sort	Braithwaite D
title	Optimal breast cancer screening strategies for older women: current perspectives
title_short	Optimal breast cancer screening strategies for older women: current perspectives
title_full	Optimal breast cancer screening strategies for older women: current perspectives
title_fullStr	Optimal breast cancer screening strategies for older women: current perspectives
title_full_unstemmed	Optimal breast cancer screening strategies for older women: current perspectives
title_sort	optimal breast cancer screening strategies for older women: current perspectives
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/3c968c5f54194b1bafe3ecad2d2ff57e
work_keys_str_mv	AT braithwaited optimalbreastcancerscreeningstrategiesforolderwomencurrentperspectives AT dembj optimalbreastcancerscreeningstrategiesforolderwomencurrentperspectives AT hendersonlm optimalbreastcancerscreeningstrategiesforolderwomencurrentperspectives
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Optimal breast cancer screening strategies for older women: current perspectives

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