STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication

ABSTRACT The life cycle of high-risk human papillomaviruses (HPVs) is dependent upon epithelial differentiation. Following infection of basal cells, HPV genomes are stably maintained at low copy numbers, and productive replication or amplification is restricted to highly differentiated suprabasal ce...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Shiyuan Hong, Shouqiang Cheng, Andre Iovane, Laimonis A. Laimins
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://doaj.org/article/3c9b0d4e0994485684d093a2d582d9a0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!