STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication
ABSTRACT The life cycle of high-risk human papillomaviruses (HPVs) is dependent upon epithelial differentiation. Following infection of basal cells, HPV genomes are stably maintained at low copy numbers, and productive replication or amplification is restricted to highly differentiated suprabasal ce...
Guardado en:
Autores principales: | Shiyuan Hong, Shouqiang Cheng, Andre Iovane, Laimonis A. Laimins |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2015
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3c9b0d4e0994485684d093a2d582d9a0 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication
por: Paul Kaminski, et al.
Publicado: (2021) -
Pathogenesis of Human Papillomaviruses Requires the ATR/p62 Autophagy-Related Pathway
por: Shiyuan Hong, et al.
Publicado: (2020) -
FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication
por: Chelsey C. Spriggs, et al.
Publicado: (2017) -
CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle
por: Apurva T. Prabhakar, et al.
Publicado: (2021) -
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation
por: Clémence Mooser, et al.
Publicado: (2020)