Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
Summary: Mechanistic insights into the role of the human microbiome in the predisposition to and treatment of disease are limited by the lack of methods to precisely add or remove microbial strains or genes from complex communities. Here, we demonstrate that engineered bacteriophage M13 can be used...
Guardado en:
Autores principales: | Kathy N. Lam, Peter Spanogiannopoulos, Paola Soto-Perez, Margaret Alexander, Matthew J. Nalley, Jordan E. Bisanz, Renuka R. Nayak, Allison M. Weakley, Feiqiao B. Yu, Peter J. Turnbaugh |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3c9ce58edeae4b90b479eb9f6c0e4cb3 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Characterization of a Type II-A CRISPR-Cas System in <italic toggle="yes">Streptococcus mutans</italic>
por: Cas Mosterd, et al.
Publicado: (2020) -
A Universal, Genomewide GuideFinder for CRISPR/Cas9 Targeting in Microbial Genomes
por: Michelle Spoto, et al.
Publicado: (2020) -
CRISPR-Cas-Mediated Phage Resistance Enhances Horizontal Gene Transfer by Transduction
por: Bridget N. J. Watson, et al.
Publicado: (2018) -
CRISPR and KRAS: a match yet to be made
por: Guzide Bender, et al.
Publicado: (2021) -
Missing a Phage: Unraveling Tripartite Symbioses within the Human Gut
por: Jeremy J. Barr
Publicado: (2019)