PacBio Amplicon Sequencing Method To Measure Pilin Antigenic Variation Frequencies of <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content>

PacBio Amplicon Sequencing Method To Measure Pilin Antigenic Variation Frequencies of <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content>

ABSTRACT Gene diversification is a common mechanism pathogens use to alter surface structures to aid in immune avoidance. Neisseria gonorrhoeae uses a gene conversion-based diversification system to alter the primary sequence of the gene encoding the major subunit of the pilus, pilE. Antigenic varia...

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Bibliographic Details
Main Authors: Egon A. Ozer, Lauren L. Prister, Shaohui Yin, Billy H. Ward, Stanimir Ivanov, H Steven Seifert
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
antigenic variation
Pacific Biosciences sequencing
amplicon sequencing
gene diversification
Microbiology
QR1-502
Online Access:https://doaj.org/article/3c9ef33863f14e60b4c2a807535a0653
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