CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.

CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.

<h4>Background</h4>The cyclic nucleotides cyclic adenosine-3',5'-monophosphate (cAMP) and cyclic guanosine-3',5'-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) an...

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Autores principales: Patrick Oeckl, Petra Steinacker, Stefan Lehnert, Sarah Jesse, Hans A Kretzschmar, Albert C Ludolph, Markus Otto, Boris Ferger
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/3ca108ae1354458b855b29fa89919062
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