m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2

Several functions have been proposed for m6A in RNA metabolism, yet little is known regarding the specific functions of individual m6A readers. Here, the authors observe that the m6A reader YTHDC2 — which contains an RNA helicase domain — acts on the coding region to promotes mRNA translation by res...

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Autores principales: Yuanhui Mao, Leiming Dong, Xiao-Min Liu, Jiayin Guo, Honghui Ma, Bin Shen, Shu-Bing Qian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3ca83b1462a8473fb1ee44b8fa43183d
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