Robust Expression of Functional NMDA Receptors in Human Induced Pluripotent Stem Cell-Derived Neuronal Cultures Using an Accelerated Protocol

Robust Expression of Functional NMDA Receptors in Human Induced Pluripotent Stem Cell-Derived Neuronal Cultures Using an Accelerated Protocol

N-methyl-D-aspartate (NMDA) receptors are critical for higher-order nervous system function, but in previously published protocols to convert human induced pluripotent stem cells (iPSCs) to mature neurons, functional NMDA receptors (NMDARs) are often either not reported or take an extended time to d...

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Autores principales: Jacob B. Ruden, Mrinalini Dixit, José C. Zepeda, Brad A. Grueter, Laura L. Dugan
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
calcium flux
induced pluripotent stem cells (iPSCs)
neural progenitor cells (NPCs)
neurons
NMDA receptors
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Acceso en línea:https://doaj.org/article/3cabc6151cc24a2b9af9c70870951f28
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