Caspase-1 Inhibitor Reduces Pyroptosis Induced by Brain Death in Kidney

Brain death (BD) induces an organ-level inflammatory response. However, the underlying mechanisms have not been fully elucidated. Here, we investigated the role of caspase-1-mediated pyroptosis in BD-induced kidney injury in rats. A BD model was established in Sprague-Dawley rats. The rats were intr...

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Auteurs principaux: Weifeng Liu, Dongjing Yang, Jihua Shi, Peihao Wen, Jiakai Zhang, Zhihui Wang, Bowen Hu, Xiaoyi Shi, Shengli Cao, Wenzhi Guo, Shuijun Zhang
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/3cac53ad661540d7b44127f4cbefa0f4
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