In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes

In vitro CSC-derived cardiomyocytes exhibit the typical microRNA-mRNA blueprint of endogenous cardiomyocytes

Scalise et al. examine the mRNAome and miRNAome of cardiomyocytes differentiated from murine adult cardiac stem cells (CSCs). Their results show that the differentiation process follows a trajectory of miRNA/mRNA expression that resembles that of adult cardiomyocytes.

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Detalles Bibliográficos
Autores principales: Mariangela Scalise, Fabiola Marino, Luca Salerno, Teresa Mancuso, Donato Cappetta, Antonella Barone, Elvira Immacolata Parrotta, Annalaura Torella, Domenico Palumbo, Pierangelo Veltri, Antonella De Angelis, Liberato Berrino, Francesco Rossi, Alessandro Weisz, Marcello Rota, Konrad Urbanek, Bernardo Nadal-Ginard, Daniele Torella, Eleonora Cianflone
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/3cd4564e0a304741913001dfdd3c1641
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Descripción
Sumario:Scalise et al. examine the mRNAome and miRNAome of cardiomyocytes differentiated from murine adult cardiac stem cells (CSCs). Their results show that the differentiation process follows a trajectory of miRNA/mRNA expression that resembles that of adult cardiomyocytes.

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