Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing

In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.

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Autores principales: Stefano Mariani, Valentina Robbiano, Lucanos M. Strambini, Aline Debrassi, Gabriela Egri, Lars Dähne, Giuseppe Barillaro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3ce1e64ca68a4c3ca778db24344f2c7b
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spelling oai:doaj.org-article:3ce1e64ca68a4c3ca778db24344f2c7b2021-12-02T14:41:17ZLayer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing10.1038/s41467-018-07723-82041-1723https://doaj.org/article/3ce1e64ca68a4c3ca778db24344f2c7b2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07723-8https://doaj.org/toc/2041-1723In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.Stefano MarianiValentina RobbianoLucanos M. StrambiniAline DebrassiGabriela EgriLars DähneGiuseppe BarillaroNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefano Mariani
Valentina Robbiano
Lucanos M. Strambini
Aline Debrassi
Gabriela Egri
Lars Dähne
Giuseppe Barillaro
Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
description In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.
format article
author Stefano Mariani
Valentina Robbiano
Lucanos M. Strambini
Aline Debrassi
Gabriela Egri
Lars Dähne
Giuseppe Barillaro
author_facet Stefano Mariani
Valentina Robbiano
Lucanos M. Strambini
Aline Debrassi
Gabriela Egri
Lars Dähne
Giuseppe Barillaro
author_sort Stefano Mariani
title Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_short Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_full Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_fullStr Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_full_unstemmed Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_sort layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/3ce1e64ca68a4c3ca778db24344f2c7b
work_keys_str_mv AT stefanomariani layerbylayerbiofunctionalizationofnanostructuredporoussiliconforhighsensitivityandhighselectivitylabelfreeaffinitybiosensing
AT valentinarobbiano layerbylayerbiofunctionalizationofnanostructuredporoussiliconforhighsensitivityandhighselectivitylabelfreeaffinitybiosensing
AT lucanosmstrambini layerbylayerbiofunctionalizationofnanostructuredporoussiliconforhighsensitivityandhighselectivitylabelfreeaffinitybiosensing
AT alinedebrassi layerbylayerbiofunctionalizationofnanostructuredporoussiliconforhighsensitivityandhighselectivitylabelfreeaffinitybiosensing
AT gabrielaegri layerbylayerbiofunctionalizationofnanostructuredporoussiliconforhighsensitivityandhighselectivitylabelfreeaffinitybiosensing
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