COVID-19 reinfection: the role of natural immunity, vaccines, and variants
The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 re...
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Taylor & Francis Group
2021
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oai:doaj.org-article:3ce28781f82641e39bb93308b45611362021-11-17T14:21:57ZCOVID-19 reinfection: the role of natural immunity, vaccines, and variants2000-966610.1080/20009666.2021.1974665https://doaj.org/article/3ce28781f82641e39bb93308b45611362021-11-01T00:00:00Zhttp://dx.doi.org/10.1080/20009666.2021.1974665https://doaj.org/toc/2000-9666The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 remains unexplored. In this review, we will discuss several aspects of reinfection: (a) How is COVID-19 reinfection characterized? (b) Does prior literature differentiate between reinfection and reactivation? (c) What SARS-CoV-2 strains do the vaccines target and can they protect against new strains? Larger and longer timeline studies are needed to understand reinfection risks. With the ongoing distribution of the SARS-CoV-2 vaccines to provide protection, the understanding of the possibility for SARS-CoV-2 reinfection remains critical. Abbreviations CDC: Centers for Disease ControlSARS-CoV-2: Severe acute respiratory syndrome coronavirus 2COVID-19: Coronavirus disease 2019RT-PCR: Reverse Transcription Polymerase Chain ReactionPASC: Post-Acute Sequelae of SARS-CoV-2 infectionBao Y. SciscentCaroline D. EiseleLisa HoSteven D. KingRohit JainReshma R. GolamariTaylor & Francis Grouparticlecovid-19reinfectioncovid-19 vaccinationcovid-19 immunitysars-cov-2Internal medicineRC31-1245ENJournal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 733-739 (2021) |
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covid-19 reinfection covid-19 vaccination covid-19 immunity sars-cov-2 Internal medicine RC31-1245 |
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covid-19 reinfection covid-19 vaccination covid-19 immunity sars-cov-2 Internal medicine RC31-1245 Bao Y. Sciscent Caroline D. Eisele Lisa Ho Steven D. King Rohit Jain Reshma R. Golamari COVID-19 reinfection: the role of natural immunity, vaccines, and variants |
description |
The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 remains unexplored. In this review, we will discuss several aspects of reinfection: (a) How is COVID-19 reinfection characterized? (b) Does prior literature differentiate between reinfection and reactivation? (c) What SARS-CoV-2 strains do the vaccines target and can they protect against new strains? Larger and longer timeline studies are needed to understand reinfection risks. With the ongoing distribution of the SARS-CoV-2 vaccines to provide protection, the understanding of the possibility for SARS-CoV-2 reinfection remains critical. Abbreviations CDC: Centers for Disease ControlSARS-CoV-2: Severe acute respiratory syndrome coronavirus 2COVID-19: Coronavirus disease 2019RT-PCR: Reverse Transcription Polymerase Chain ReactionPASC: Post-Acute Sequelae of SARS-CoV-2 infection |
format |
article |
author |
Bao Y. Sciscent Caroline D. Eisele Lisa Ho Steven D. King Rohit Jain Reshma R. Golamari |
author_facet |
Bao Y. Sciscent Caroline D. Eisele Lisa Ho Steven D. King Rohit Jain Reshma R. Golamari |
author_sort |
Bao Y. Sciscent |
title |
COVID-19 reinfection: the role of natural immunity, vaccines, and variants |
title_short |
COVID-19 reinfection: the role of natural immunity, vaccines, and variants |
title_full |
COVID-19 reinfection: the role of natural immunity, vaccines, and variants |
title_fullStr |
COVID-19 reinfection: the role of natural immunity, vaccines, and variants |
title_full_unstemmed |
COVID-19 reinfection: the role of natural immunity, vaccines, and variants |
title_sort |
covid-19 reinfection: the role of natural immunity, vaccines, and variants |
publisher |
Taylor & Francis Group |
publishDate |
2021 |
url |
https://doaj.org/article/3ce28781f82641e39bb93308b4561136 |
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