Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours

The luminal gastrointestinal tract carcinomas are one of the major causes of cancer-related deaths. To improve overall survival, the current trend is to combine targeted therapeutic agents with conventional chemotherapies. Major trials have shown survival benefits with this approach and many more tr...

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Autores principales: Prasenjit Das, Lalita Mehra
Formato: article
Lenguaje:EN
Publicado: Wolters Kluwer Medknow Publications 2021
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Acceso en línea:https://doaj.org/article/3ce5afa36fb247ecada62d44716de58a
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spelling oai:doaj.org-article:3ce5afa36fb247ecada62d44716de58a2021-12-02T17:28:22ZApplicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours0377-492910.4103/ijpm.ijpm_260_21https://doaj.org/article/3ce5afa36fb247ecada62d44716de58a2021-01-01T00:00:00Zhttp://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=2;epage=3;aulast=Dashttps://doaj.org/toc/0377-4929The luminal gastrointestinal tract carcinomas are one of the major causes of cancer-related deaths. To improve overall survival, the current trend is to combine targeted therapeutic agents with conventional chemotherapies. Major trials have shown survival benefits with this approach and many more trials are being undertaken. However, pathologists often get perplexed by different methods of interpretation and reporting of these stains, vital for deciding therapeutic approaches.Prasenjit DasLalita MehraWolters Kluwer Medknow Publicationsarticlecolorectal carcinomaesophageal carcinomagastric carcinomaher2/neuimmunohistochemistrypd-l1PathologyRB1-214MicrobiologyQR1-502ENIndian Journal of Pathology and Microbiology, Vol 64, Iss 5, Pp 2-3 (2021)
institution DOAJ
collection DOAJ
language EN
topic colorectal carcinoma
esophageal carcinoma
gastric carcinoma
her2/neu
immunohistochemistry
pd-l1
Pathology
RB1-214
Microbiology
QR1-502
spellingShingle colorectal carcinoma
esophageal carcinoma
gastric carcinoma
her2/neu
immunohistochemistry
pd-l1
Pathology
RB1-214
Microbiology
QR1-502
Prasenjit Das
Lalita Mehra
Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
description The luminal gastrointestinal tract carcinomas are one of the major causes of cancer-related deaths. To improve overall survival, the current trend is to combine targeted therapeutic agents with conventional chemotherapies. Major trials have shown survival benefits with this approach and many more trials are being undertaken. However, pathologists often get perplexed by different methods of interpretation and reporting of these stains, vital for deciding therapeutic approaches.
format article
author Prasenjit Das
Lalita Mehra
author_facet Prasenjit Das
Lalita Mehra
author_sort Prasenjit Das
title Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
title_short Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
title_full Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
title_fullStr Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
title_full_unstemmed Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
title_sort applicability and interpretation of her2/neu & pd-l1 stains in gastrointestinal tract tumours
publisher Wolters Kluwer Medknow Publications
publishDate 2021
url https://doaj.org/article/3ce5afa36fb247ecada62d44716de58a
work_keys_str_mv AT prasenjitdas applicabilityandinterpretationofher2neupdl1stainsingastrointestinaltracttumours
AT lalitamehra applicabilityandinterpretationofher2neupdl1stainsingastrointestinaltracttumours
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