Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours
The luminal gastrointestinal tract carcinomas are one of the major causes of cancer-related deaths. To improve overall survival, the current trend is to combine targeted therapeutic agents with conventional chemotherapies. Major trials have shown survival benefits with this approach and many more tr...
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Wolters Kluwer Medknow Publications
2021
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oai:doaj.org-article:3ce5afa36fb247ecada62d44716de58a2021-12-02T17:28:22ZApplicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours0377-492910.4103/ijpm.ijpm_260_21https://doaj.org/article/3ce5afa36fb247ecada62d44716de58a2021-01-01T00:00:00Zhttp://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=5;spage=2;epage=3;aulast=Dashttps://doaj.org/toc/0377-4929The luminal gastrointestinal tract carcinomas are one of the major causes of cancer-related deaths. To improve overall survival, the current trend is to combine targeted therapeutic agents with conventional chemotherapies. Major trials have shown survival benefits with this approach and many more trials are being undertaken. However, pathologists often get perplexed by different methods of interpretation and reporting of these stains, vital for deciding therapeutic approaches.Prasenjit DasLalita MehraWolters Kluwer Medknow Publicationsarticlecolorectal carcinomaesophageal carcinomagastric carcinomaher2/neuimmunohistochemistrypd-l1PathologyRB1-214MicrobiologyQR1-502ENIndian Journal of Pathology and Microbiology, Vol 64, Iss 5, Pp 2-3 (2021) |
institution |
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DOAJ |
language |
EN |
topic |
colorectal carcinoma esophageal carcinoma gastric carcinoma her2/neu immunohistochemistry pd-l1 Pathology RB1-214 Microbiology QR1-502 |
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colorectal carcinoma esophageal carcinoma gastric carcinoma her2/neu immunohistochemistry pd-l1 Pathology RB1-214 Microbiology QR1-502 Prasenjit Das Lalita Mehra Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours |
description |
The luminal gastrointestinal tract carcinomas are one of the major causes of cancer-related deaths. To improve overall survival, the current trend is to combine targeted therapeutic agents with conventional chemotherapies. Major trials have shown survival benefits with this approach and many more trials are being undertaken. However, pathologists often get perplexed by different methods of interpretation and reporting of these stains, vital for deciding therapeutic approaches. |
format |
article |
author |
Prasenjit Das Lalita Mehra |
author_facet |
Prasenjit Das Lalita Mehra |
author_sort |
Prasenjit Das |
title |
Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours |
title_short |
Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours |
title_full |
Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours |
title_fullStr |
Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours |
title_full_unstemmed |
Applicability and interpretation of HER2/Neu & PD-L1 stains in gastrointestinal tract tumours |
title_sort |
applicability and interpretation of her2/neu & pd-l1 stains in gastrointestinal tract tumours |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2021 |
url |
https://doaj.org/article/3ce5afa36fb247ecada62d44716de58a |
work_keys_str_mv |
AT prasenjitdas applicabilityandinterpretationofher2neupdl1stainsingastrointestinaltracttumours AT lalitamehra applicabilityandinterpretationofher2neupdl1stainsingastrointestinaltracttumours |
_version_ |
1718380725791621120 |