DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

While DNA methylation and gene expression data are widely available for animal models, comprehensive data from human development is rarer. Here, the authors generated transcriptional and DNA methylation data from 21 organs during human development and 6 isogenic induced pluripotent stem cell lines.

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Autores principales:	Matthias S. Roost, Roderick C. Slieker, Monika Bialecka, Liesbeth van Iperen, Maria M. Gomes Fernandes, Nannan He, H. Eka D. Suchiman, Karoly Szuhai, Françoise Carlotti, Eelco J. P. de Koning, Christine L. Mummery, Bastiaan T. Heijmans, Susana M. Chuva de Sousa Lopes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3ce6f2a452d142e3b2266b6026a99a87
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spelling	oai:doaj.org-article:3ce6f2a452d142e3b2266b6026a99a872021-12-02T14:40:23ZDNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells10.1038/s41467-017-01077-32041-1723https://doaj.org/article/3ce6f2a452d142e3b2266b6026a99a872017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01077-3https://doaj.org/toc/2041-1723While DNA methylation and gene expression data are widely available for animal models, comprehensive data from human development is rarer. Here, the authors generated transcriptional and DNA methylation data from 21 organs during human development and 6 isogenic induced pluripotent stem cell lines.Matthias S. RoostRoderick C. SliekerMonika BialeckaLiesbeth van IperenMaria M. Gomes FernandesNannan HeH. Eka D. SuchimanKaroly SzuhaiFrançoise CarlottiEelco J. P. de KoningChristine L. MummeryBastiaan T. HeijmansSusana M. Chuva de Sousa LopesNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthias S. Roost Roderick C. Slieker Monika Bialecka Liesbeth van Iperen Maria M. Gomes Fernandes Nannan He H. Eka D. Suchiman Karoly Szuhai Françoise Carlotti Eelco J. P. de Koning Christine L. Mummery Bastiaan T. Heijmans Susana M. Chuva de Sousa Lopes DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
description	While DNA methylation and gene expression data are widely available for animal models, comprehensive data from human development is rarer. Here, the authors generated transcriptional and DNA methylation data from 21 organs during human development and 6 isogenic induced pluripotent stem cell lines.
format	article
author	Matthias S. Roost Roderick C. Slieker Monika Bialecka Liesbeth van Iperen Maria M. Gomes Fernandes Nannan He H. Eka D. Suchiman Karoly Szuhai Françoise Carlotti Eelco J. P. de Koning Christine L. Mummery Bastiaan T. Heijmans Susana M. Chuva de Sousa Lopes
author_facet	Matthias S. Roost Roderick C. Slieker Monika Bialecka Liesbeth van Iperen Maria M. Gomes Fernandes Nannan He H. Eka D. Suchiman Karoly Szuhai Françoise Carlotti Eelco J. P. de Koning Christine L. Mummery Bastiaan T. Heijmans Susana M. Chuva de Sousa Lopes
author_sort	Matthias S. Roost
title	DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
title_short	DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
title_full	DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
title_fullStr	DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
title_full_unstemmed	DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
title_sort	dna methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3ce6f2a452d142e3b2266b6026a99a87
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DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

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