DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

While DNA methylation and gene expression data are widely available for animal models, comprehensive data from human development is rarer. Here, the authors generated transcriptional and DNA methylation data from 21 organs during human development and 6 isogenic induced pluripotent stem cell lines.

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Detalles Bibliográficos
Autores principales: Matthias S. Roost, Roderick C. Slieker, Monika Bialecka, Liesbeth van Iperen, Maria M. Gomes Fernandes, Nannan He, H. Eka D. Suchiman, Karoly Szuhai, Françoise Carlotti, Eelco J. P. de Koning, Christine L. Mummery, Bastiaan T. Heijmans, Susana M. Chuva de Sousa Lopes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/3ce6f2a452d142e3b2266b6026a99a87
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