Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening

Establishment and maintenance of apico-basal polarity in epithelial organs needs to be tightly coupled with cell division. Here the authors show that the Rab35 GTPase tethers intracellular vesicles containing key apical determinants at the cleavage site, connecting cytokinesis to apico-basal polarit...

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Autores principales: Kerstin Klinkert, Murielle Rocancourt, Anne Houdusse, Arnaud Echard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3ce83f39d62f4accac49fe2389188251
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spelling oai:doaj.org-article:3ce83f39d62f4accac49fe23891882512021-12-02T15:34:09ZRab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening10.1038/ncomms111662041-1723https://doaj.org/article/3ce83f39d62f4accac49fe23891882512016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11166https://doaj.org/toc/2041-1723Establishment and maintenance of apico-basal polarity in epithelial organs needs to be tightly coupled with cell division. Here the authors show that the Rab35 GTPase tethers intracellular vesicles containing key apical determinants at the cleavage site, connecting cytokinesis to apico-basal polarity.Kerstin KlinkertMurielle RocancourtAnne HoudusseArnaud EchardNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kerstin Klinkert
Murielle Rocancourt
Anne Houdusse
Arnaud Echard
Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
description Establishment and maintenance of apico-basal polarity in epithelial organs needs to be tightly coupled with cell division. Here the authors show that the Rab35 GTPase tethers intracellular vesicles containing key apical determinants at the cleavage site, connecting cytokinesis to apico-basal polarity.
format article
author Kerstin Klinkert
Murielle Rocancourt
Anne Houdusse
Arnaud Echard
author_facet Kerstin Klinkert
Murielle Rocancourt
Anne Houdusse
Arnaud Echard
author_sort Kerstin Klinkert
title Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
title_short Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
title_full Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
title_fullStr Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
title_full_unstemmed Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
title_sort rab35 gtpase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/3ce83f39d62f4accac49fe2389188251
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AT annehoudusse rab35gtpasecouplescelldivisionwithinitiationofepithelialapicobasalpolarityandlumenopening
AT arnaudechard rab35gtpasecouplescelldivisionwithinitiationofepithelialapicobasalpolarityandlumenopening
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