Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the ag...
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Nature Portfolio
2019
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oai:doaj.org-article:3cea5d86f3b244b58dabced82d0db6fd2021-12-02T15:35:56ZDisentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI10.1038/s41467-019-11319-12041-1723https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11319-1https://doaj.org/toc/2041-1723MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the aging human brain.Shir FiloOshrat ShtangelNoga SalamonAdi KolBatsheva WeisingerSagiv ShifmanAviv A. MezerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Shir Filo Oshrat Shtangel Noga Salamon Adi Kol Batsheva Weisinger Sagiv Shifman Aviv A. Mezer Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI |
description |
MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the aging human brain. |
format |
article |
author |
Shir Filo Oshrat Shtangel Noga Salamon Adi Kol Batsheva Weisinger Sagiv Shifman Aviv A. Mezer |
author_facet |
Shir Filo Oshrat Shtangel Noga Salamon Adi Kol Batsheva Weisinger Sagiv Shifman Aviv A. Mezer |
author_sort |
Shir Filo |
title |
Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI |
title_short |
Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI |
title_full |
Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI |
title_fullStr |
Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI |
title_full_unstemmed |
Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI |
title_sort |
disentangling molecular alterations from water-content changes in the aging human brain using quantitative mri |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd |
work_keys_str_mv |
AT shirfilo disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT oshratshtangel disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT nogasalamon disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT adikol disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT batshevaweisinger disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT sagivshifman disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT avivamezer disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri |
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1718386405242044416 |