Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI

MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the ag...

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Auteurs principaux:	Shir Filo, Oshrat Shtangel, Noga Salamon, Adi Kol, Batsheva Weisinger, Sagiv Shifman, Aviv A. Mezer
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd
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spelling	oai:doaj.org-article:3cea5d86f3b244b58dabced82d0db6fd2021-12-02T15:35:56ZDisentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI10.1038/s41467-019-11319-12041-1723https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11319-1https://doaj.org/toc/2041-1723MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the aging human brain.Shir FiloOshrat ShtangelNoga SalamonAdi KolBatsheva WeisingerSagiv ShifmanAviv A. MezerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shir Filo Oshrat Shtangel Noga Salamon Adi Kol Batsheva Weisinger Sagiv Shifman Aviv A. Mezer Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
description	MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the aging human brain.
format	article
author	Shir Filo Oshrat Shtangel Noga Salamon Adi Kol Batsheva Weisinger Sagiv Shifman Aviv A. Mezer
author_facet	Shir Filo Oshrat Shtangel Noga Salamon Adi Kol Batsheva Weisinger Sagiv Shifman Aviv A. Mezer
author_sort	Shir Filo
title	Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_short	Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_full	Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_fullStr	Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_full_unstemmed	Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_sort	disentangling molecular alterations from water-content changes in the aging human brain using quantitative mri
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd
work_keys_str_mv	AT shirfilo disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT oshratshtangel disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT nogasalamon disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT adikol disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT batshevaweisinger disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT sagivshifman disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri AT avivamezer disentanglingmolecularalterationsfromwatercontentchangesintheaginghumanbrainusingquantitativemri
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Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI

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