Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI

MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the ag...

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Autores principales: Shir Filo, Oshrat Shtangel, Noga Salamon, Adi Kol, Batsheva Weisinger, Sagiv Shifman, Aviv A. Mezer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd
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spelling oai:doaj.org-article:3cea5d86f3b244b58dabced82d0db6fd2021-12-02T15:35:56ZDisentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI10.1038/s41467-019-11319-12041-1723https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11319-1https://doaj.org/toc/2041-1723MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the aging human brain.Shir FiloOshrat ShtangelNoga SalamonAdi KolBatsheva WeisingerSagiv ShifmanAviv A. MezerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shir Filo
Oshrat Shtangel
Noga Salamon
Adi Kol
Batsheva Weisinger
Sagiv Shifman
Aviv A. Mezer
Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
description MRI has been used for the non-invasive imaging of human brain aging but is sensitive to both tissue molecular composition and water content. Here the authors present a quantitative MRI method that discriminates these factors and describe region-specific changes in the molecular composition of the aging human brain.
format article
author Shir Filo
Oshrat Shtangel
Noga Salamon
Adi Kol
Batsheva Weisinger
Sagiv Shifman
Aviv A. Mezer
author_facet Shir Filo
Oshrat Shtangel
Noga Salamon
Adi Kol
Batsheva Weisinger
Sagiv Shifman
Aviv A. Mezer
author_sort Shir Filo
title Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_short Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_full Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_fullStr Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_full_unstemmed Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI
title_sort disentangling molecular alterations from water-content changes in the aging human brain using quantitative mri
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3cea5d86f3b244b58dabced82d0db6fd
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