Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey

Abstract There are limited data on chronic kidney disease of unknown etiology (CKDu) from Southeast Asia. Initially described in working age men, a common approach to detect CKDu that includes all adults has recently been proposed. We determined the prevalence, and risk factors for CKDu using data f...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wichai Aekplakorn, Suwat Chariyalertsak, Pattapong Kessomboon, Sawitri Assanangkornchai, Surasak Taneepanichskul, Nareemarn Neelapaichit, Anchalee Chittamma, Chagriya Kitiyakara
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3cf5832e5a024fd29a8b226572b18019
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3cf5832e5a024fd29a8b226572b18019
record_format	dspace
spelling	oai:doaj.org-article:3cf5832e5a024fd29a8b226572b180192021-11-08T10:53:08ZWomen and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey10.1038/s41598-021-00694-92045-2322https://doaj.org/article/3cf5832e5a024fd29a8b226572b180192021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-00694-9https://doaj.org/toc/2045-2322Abstract There are limited data on chronic kidney disease of unknown etiology (CKDu) from Southeast Asia. Initially described in working age men, a common approach to detect CKDu that includes all adults has recently been proposed. We determined the prevalence, and risk factors for CKDu using data from a cross-sectional, nationally representative survey of the adult population of Thailand. We used a proxy for CKDu as age < 70 with impaired kidney function (eGFR < 60) in the absence of diabetes and hypertension (CKDu1) and heavy proteinuria (CKDu2). Prevalence estimates were probability-weighted for the Thai population. The associations between risk factors and CKDu or elderly subjects with eGFR < 60 without traditional causes were assessed by multivariable logistic regression. Of 17,329 subjects, the prevalence were: eGFR < 60, 5.3%; CKDu1 0.78%; CKDu2, 0.75%. CKDu differed by 4.3-folds between regions. Women, farmers/laborers, older age, gout, painkillers, rural area, and stones were independent risk factors for CKDu. Women, age, rural, gout, painkillers were significant risk factors for both CKDu and elderly subjects. These data collected using standardized methodology showed that the prevalence of CKDu in Thailand was low overall, although some regions had higher risk. Unlike other countries, Thai women had a two-fold higher risk of CKDu.Wichai AekplakornSuwat ChariyalertsakPattapong KessomboonSawitri AssanangkornchaiSurasak TaneepanichskulNareemarn NeelapaichitAnchalee ChittammaChagriya KitiyakaraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Wichai Aekplakorn Suwat Chariyalertsak Pattapong Kessomboon Sawitri Assanangkornchai Surasak Taneepanichskul Nareemarn Neelapaichit Anchalee Chittamma Chagriya Kitiyakara Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey
description	Abstract There are limited data on chronic kidney disease of unknown etiology (CKDu) from Southeast Asia. Initially described in working age men, a common approach to detect CKDu that includes all adults has recently been proposed. We determined the prevalence, and risk factors for CKDu using data from a cross-sectional, nationally representative survey of the adult population of Thailand. We used a proxy for CKDu as age < 70 with impaired kidney function (eGFR < 60) in the absence of diabetes and hypertension (CKDu1) and heavy proteinuria (CKDu2). Prevalence estimates were probability-weighted for the Thai population. The associations between risk factors and CKDu or elderly subjects with eGFR < 60 without traditional causes were assessed by multivariable logistic regression. Of 17,329 subjects, the prevalence were: eGFR < 60, 5.3%; CKDu1 0.78%; CKDu2, 0.75%. CKDu differed by 4.3-folds between regions. Women, farmers/laborers, older age, gout, painkillers, rural area, and stones were independent risk factors for CKDu. Women, age, rural, gout, painkillers were significant risk factors for both CKDu and elderly subjects. These data collected using standardized methodology showed that the prevalence of CKDu in Thailand was low overall, although some regions had higher risk. Unlike other countries, Thai women had a two-fold higher risk of CKDu.
format	article
author	Wichai Aekplakorn Suwat Chariyalertsak Pattapong Kessomboon Sawitri Assanangkornchai Surasak Taneepanichskul Nareemarn Neelapaichit Anchalee Chittamma Chagriya Kitiyakara
author_facet	Wichai Aekplakorn Suwat Chariyalertsak Pattapong Kessomboon Sawitri Assanangkornchai Surasak Taneepanichskul Nareemarn Neelapaichit Anchalee Chittamma Chagriya Kitiyakara
author_sort	Wichai Aekplakorn
title	Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey
title_short	Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey
title_full	Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey
title_fullStr	Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey
title_full_unstemmed	Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey
title_sort	women and other risk factors for chronic kidney disease of unknown etiology in thailand: national health examination v survey
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3cf5832e5a024fd29a8b226572b18019
work_keys_str_mv	AT wichaiaekplakorn womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey AT suwatchariyalertsak womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey AT pattapongkessomboon womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey AT sawitriassanangkornchai womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey AT surasaktaneepanichskul womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey AT nareemarnneelapaichit womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey AT anchaleechittamma womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey AT chagriyakitiyakara womenandotherriskfactorsforchronickidneydiseaseofunknownetiologyinthailandnationalhealthexaminationvsurvey
_version_	1718442514335137792

Women and other risk factors for chronic kidney disease of unknown etiology in Thailand: National Health Examination V Survey

Ejemplares similares