Targeting ERK induced cell death and p53/ROS-dependent protective autophagy in colorectal cancer

Abstract In recent years, many studies have shown that autophagy plays a vital role in the resistance of tumor chemotherapy. However, the interaction between autophagy and cell death has not yet been clarified. In this study, a new specific ERK inhibitor CC90003 was found to suppress colorectal canc...

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Auteurs principaux: Wunan Mi, Chuyue Wang, Guang Luo, Jiehan Li, Yizheng Zhang, Meimei Jiang, Chuchu Zhang, Nannan Liu, Xinxiu Jiang, Ge Yang, Lingling Zhang, Ge Zhang, Yingjie Zhang, Yang Fu
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
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Accès en ligne:https://doaj.org/article/3cfc88cc58bf4b919462019446ba917f
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