Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial

Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial

Hormonal contraception may alter women’s susceptibility to HIV. Here, the authors report the results of a randomized clinical trial substudy assessing the effects of injectable Net-En, oral contraceptives (COC) and Nuvaring on vaginal microbiota and cytokines, associating COC with lower microbial di...

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Autores principales: Christina Balle, Iyaloo N. Konstantinus, Shameem Z. Jaumdally, Enock Havyarimana, Katie Lennard, Rachel Esra, Shaun L. Barnabas, Anna-Ursula Happel, Zoe Moodie, Katherine Gill, Tanya Pidwell, Ulas Karaoz, Eoin Brodie, Venessa Maseko, Hoyam Gamieldien, Steven E. Bosinger, Landon Myer, Linda-Gail Bekker, Jo-Ann S. Passmore, Heather B. Jaspan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Q
Acceso en línea:https://doaj.org/article/3d0099497abb46188c654efca2cd2cb7
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spelling oai:doaj.org-article:3d0099497abb46188c654efca2cd2cb72021-12-02T14:41:26ZHormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial10.1038/s41467-020-19382-92041-1723https://doaj.org/article/3d0099497abb46188c654efca2cd2cb72020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19382-9https://doaj.org/toc/2041-1723Hormonal contraception may alter women’s susceptibility to HIV. Here, the authors report the results of a randomized clinical trial substudy assessing the effects of injectable Net-En, oral contraceptives (COC) and Nuvaring on vaginal microbiota and cytokines, associating COC with lower microbial diversity and Nuvaring with increased inflammation.Christina BalleIyaloo N. KonstantinusShameem Z. JaumdallyEnock HavyarimanaKatie LennardRachel EsraShaun L. BarnabasAnna-Ursula HappelZoe MoodieKatherine GillTanya PidwellUlas KaraozEoin BrodieVenessa MasekoHoyam GamieldienSteven E. BosingerLandon MyerLinda-Gail BekkerJo-Ann S. PassmoreHeather B. JaspanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Christina Balle
Iyaloo N. Konstantinus
Shameem Z. Jaumdally
Enock Havyarimana
Katie Lennard
Rachel Esra
Shaun L. Barnabas
Anna-Ursula Happel
Zoe Moodie
Katherine Gill
Tanya Pidwell
Ulas Karaoz
Eoin Brodie
Venessa Maseko
Hoyam Gamieldien
Steven E. Bosinger
Landon Myer
Linda-Gail Bekker
Jo-Ann S. Passmore
Heather B. Jaspan
Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
description Hormonal contraception may alter women’s susceptibility to HIV. Here, the authors report the results of a randomized clinical trial substudy assessing the effects of injectable Net-En, oral contraceptives (COC) and Nuvaring on vaginal microbiota and cytokines, associating COC with lower microbial diversity and Nuvaring with increased inflammation.
format article
author Christina Balle
Iyaloo N. Konstantinus
Shameem Z. Jaumdally
Enock Havyarimana
Katie Lennard
Rachel Esra
Shaun L. Barnabas
Anna-Ursula Happel
Zoe Moodie
Katherine Gill
Tanya Pidwell
Ulas Karaoz
Eoin Brodie
Venessa Maseko
Hoyam Gamieldien
Steven E. Bosinger
Landon Myer
Linda-Gail Bekker
Jo-Ann S. Passmore
Heather B. Jaspan
author_facet Christina Balle
Iyaloo N. Konstantinus
Shameem Z. Jaumdally
Enock Havyarimana
Katie Lennard
Rachel Esra
Shaun L. Barnabas
Anna-Ursula Happel
Zoe Moodie
Katherine Gill
Tanya Pidwell
Ulas Karaoz
Eoin Brodie
Venessa Maseko
Hoyam Gamieldien
Steven E. Bosinger
Landon Myer
Linda-Gail Bekker
Jo-Ann S. Passmore
Heather B. Jaspan
author_sort Christina Balle
title Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
title_short Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
title_full Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
title_fullStr Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
title_full_unstemmed Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
title_sort hormonal contraception alters vaginal microbiota and cytokines in south african adolescents in a randomized trial
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/3d0099497abb46188c654efca2cd2cb7
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