CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA

Abstract. The aim of the present work was to evaluate the contents of some lymphocyte sub-populations in peripheral blood of the children with tumors of hematopoietic and lymphoid tissues, depending on infectious complication of cytostatic therapy and neutropenia. In all children undergoing cytostat...

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Autores principales:	M. V. Peshikova, I. I. Dolgushin, O. L. Kolesnikov, N. N. Rusanova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	leukemia lymphoma children infection immunity Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/3d039a047ee947a68e6d2ab47bf97583
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spelling	oai:doaj.org-article:3d039a047ee947a68e6d2ab47bf975832021-11-18T08:03:43ZCONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA1563-06252313-741X10.15789/1563-0625-2005-5-6-551-556https://doaj.org/article/3d039a047ee947a68e6d2ab47bf975832014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/622https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The aim of the present work was to evaluate the contents of some lymphocyte sub-populations in peripheral blood of the children with tumors of hematopoietic and lymphoid tissues, depending on infectious complication of cytostatic therapy and neutropenia. In all children undergoing cytostatic therapy for acute lympho-blastic leukemia and non-B cell non-Hodgkinґs lymphomas, we found significant decrease in the numbers of CD95 lymphocytes, absolute amounts of natural killer cells (CD16, CD56-lymphocytes) and activated lymphocytes (СD11b, HLA-DR-cells), irrespective of neutrophile numbers in their blood and infectious complications. However, absolute number of CD25- lymphocytes was significantly decreased in the children with neutropenia. Relative contents of CD16, CD56, СD11b, HLA-DR, CD25-lymphocytes did not significantly differ from those in healthy children, or they were found to be significantly increased.M. V. PeshikovaI. I. DolgushinO. L. KolesnikovN. N. RusanovaSPb RAACIarticleleukemialymphomachildreninfectionimmunityImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 5-6, Pp 551-556 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	leukemia lymphoma children infection immunity Immunologic diseases. Allergy RC581-607
spellingShingle	leukemia lymphoma children infection immunity Immunologic diseases. Allergy RC581-607 M. V. Peshikova I. I. Dolgushin O. L. Kolesnikov N. N. Rusanova CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA
description	Abstract. The aim of the present work was to evaluate the contents of some lymphocyte sub-populations in peripheral blood of the children with tumors of hematopoietic and lymphoid tissues, depending on infectious complication of cytostatic therapy and neutropenia. In all children undergoing cytostatic therapy for acute lympho-blastic leukemia and non-B cell non-Hodgkinґs lymphomas, we found significant decrease in the numbers of CD95 lymphocytes, absolute amounts of natural killer cells (CD16, CD56-lymphocytes) and activated lymphocytes (СD11b, HLA-DR-cells), irrespective of neutrophile numbers in their blood and infectious complications. However, absolute number of CD25- lymphocytes was significantly decreased in the children with neutropenia. Relative contents of CD16, CD56, СD11b, HLA-DR, CD25-lymphocytes did not significantly differ from those in healthy children, or they were found to be significantly increased.
format	article
author	M. V. Peshikova I. I. Dolgushin O. L. Kolesnikov N. N. Rusanova
author_facet	M. V. Peshikova I. I. Dolgushin O. L. Kolesnikov N. N. Rusanova
author_sort	M. V. Peshikova
title	CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA
title_short	CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA
title_full	CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA
title_fullStr	CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA
title_full_unstemmed	CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA
title_sort	contents of lymphocyte sub-populations in the children with acute leukemia and lymphomas dependent on infectious complication and neutropenia
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/3d039a047ee947a68e6d2ab47bf97583
work_keys_str_mv	AT mvpeshikova contentsoflymphocytesubpopulationsinthechildrenwithacuteleukemiaandlymphomasdependentoninfectiouscomplicationandneutropenia AT iidolgushin contentsoflymphocytesubpopulationsinthechildrenwithacuteleukemiaandlymphomasdependentoninfectiouscomplicationandneutropenia AT olkolesnikov contentsoflymphocytesubpopulationsinthechildrenwithacuteleukemiaandlymphomasdependentoninfectiouscomplicationandneutropenia AT nnrusanova contentsoflymphocytesubpopulationsinthechildrenwithacuteleukemiaandlymphomasdependentoninfectiouscomplicationandneutropenia
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CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA

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