Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH

Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH

Abstract miRNAs are involved in the development of metabolic associated fatty liver disease (MAFLD) and nonalcoholic steatohepatitis (NASH). We aimed to evaluate modifications by prolonged-release pirfenidone (PR-PFD) on key hepatic miRNAs expression in a MAFLD/NASH model. First, male C57BL/6J mice...

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Main Authors: Rebeca Escutia-Gutiérrez, J. Samael Rodríguez-Sanabria, C. Alejandra Monraz-Méndez, Jesús García-Bañuelos, Arturo Santos-García, Ana Sandoval-Rodríguez, Juan Armendáriz-Borunda
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/3d0a5ea6aa3f4130aece7fe0791813bc
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https://doaj.org/article/3d0a5ea6aa3f4130aece7fe0791813bc

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